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    metallo-dependent hydrolase superfamily protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852587, updated on 9-Dec-2024

    Summary

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    Official Full Name
    metallo-dependent hydrolase superfamily protein
    Primary source
    SGD:S000000488
    Locus tag
    YBR284W
    See related
    AllianceGenome:SGD:S000000488; FungiDB:YBR284W; VEuPathDB:YBR284W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be located in membrane. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (771239..773632)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene mitochondrial 54S ribosomal protein YmL27 Neighboring gene Ssh1p Neighboring gene Hab1p Neighboring gene aminopeptidase Y

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The sequence of a 32,420 bp segment located on the right arm of chromosome II from Saccharomyces cerevisiae. Holmstrøm K, et al. Yeast, 1994 Apr. PMID 8091861
    2. Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae. Saint-Marc C, et al. Genetics, 2009 Oct. PMID 19635936, Free PMC Article
    3. Generation of null alleles for the functional analysis of six genes from the right arm of Saccharomyces cerevisiae chromosome II. Dueñas E, et al. Yeast, 1999 May. PMID 10341424
    4. Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Xie MW, et al. Proc Natl Acad Sci U S A, 2005 May 17. PMID 15883373, Free PMC Article
    5. Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. Gatbonton T, et al. PLoS Genet, 2006 Mar. PMID 16552446, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    metallo-dependent hydrolase superfamily protein
    NP_009843.3
    • Putative metallo-dependent hydrolase superfamily protein; similar to AMP deaminases but lacks key catalytic residues and does not rescue purine nucleotide metabolic defect of quadruple aah1 ade8 amd1 his1 mutant; null mutant exhibits longer telomeres, altered Ty mobility, decreased resistance to rapamycin and wortmannin; induced in response to hydrostatic pressure; not an essential gene; YBR284W has a paralog, YJL070C, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      771239..773632
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178632.3 → NP_009843.3  TPA: metallo-dependent hydrolase superfamily protein [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009843.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQS9, P38150
      UniProtKB/TrEMBL
      G2W9T7, N1P790
      Conserved Domains (1) summary
      COG1816
      Location:341 → 748
      Add; Adenosine deaminase [Nucleotide transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38150.1

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