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    RPL18B ribosomal 60S subunit protein L18B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855415, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPL18B
    Official Full Name
    ribosomal 60S subunit protein L18B
    Primary source
    SGD:S000005245
    Locus tag
    YNL301C
    See related
    AllianceGenome:SGD:S000005245; FungiDB:YNL301C; VEuPathDB:YNL301C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RP28B
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 18. Orthologous to human RPL18 (ribosomal protein L18). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPL18B in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    2
    Sequence:
    Chromosome: XIV; NC_001146.8 (63570..64562, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Rab family GTPase YPT11 Neighboring gene ribosomal 40S subunit protein S19B Neighboring gene Tos6p Neighboring gene non-canonical poly(A) polymerase TRF5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of a duplicated linked pair of ribosomal protein genes in Saccharomyces cerevisiae. Donovan DM, et al. Mol Cell Biol, 1990 Nov. PMID 2233736, Free PMC Article
    2. Genetic mapping of two pairs of linked ribosomal protein genes in Saccharomyces cerevisiae. Papciak SM, et al. Curr Genet, 1987. PMID 3329973
    3. A QPCR-based reporter system to study post-transcriptional regulation via the 3' untranslated region of mRNA in Saccharomyces cerevisiae. Lind K, et al. Yeast, 2009 Jul. PMID 19507146
    4. Structure and organization of two linked ribosomal protein genes in yeast. Molenaar CM, et al. Nucleic Acids Res, 1984 Oct 11. PMID 6387623, Free PMC Article
    5. Coordinated Ribosomal L4 Protein Assembly into the Pre-Ribosome Is Regulated by Its Eukaryote-Specific Extension. Stelter P, et al. Mol Cell, 2015 Jun 4. PMID 25936803, Free PMC Article

    See all (77) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L18B
    NP_014098.1
    • Ribosomal 60S subunit protein L18B; homologous to mammalian ribosomal protein L18, no bacterial homolog; RPL18B has a paralog, RPL18A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      63570..64562 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183139.1 → NP_014098.1  TPA: ribosomal 60S subunit protein L18B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014098.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0P3, P07279, P0CX49, P0CX50
      UniProtKB/TrEMBL
      A6ZN91, B3LIU6, C8ZGM2, G2WLG7, N1NWY0
      Conserved Domains (1) summary
      pfam17135
      Location:2 → 186
      Ribosomal_L18; Ribosomal protein 60S L18 and 50S L18e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CX49.1
    P0CX50.1

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