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    mcm5 MCM complex subunit Mcm5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542477, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mcm5
    Official Full Name
    MCM complex subunit Mcm5
    Primary source
    PomBase:SPAC1B2.05
    Locus tag
    SPOM_SPAC1B2.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    nda4; SPAC3F10.01
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    Genomic context

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    See mcm5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (2815661..2820694)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cytochrome c oxidase subunit VI Neighboring gene plasma membrane potassium ion transmembrane transporter Trk1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glycine--tRNA (Gly) ligase Grs1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fission yeast Nda1 and Nda4, MCM homologs required for DNA replication, are constitutive nuclear proteins. Okishio N, et al. J Cell Sci, 1996 Feb. PMID 8838655
    2. Schizosaccharomyces pombe Mcm3p, an essential nuclear protein, associates tightly with Nda4p (Mcm5p). Sherman DA, et al. Nucleic Acids Res, 1998 Sep 1. PMID 9705504, Free PMC Article
    3. Identification of sna41 gene, which is the suppressor of nda4 mutation and is involved in DNA replication in Schizosaccharomyces pombe. Miyake S, et al. Genes Cells, 1998 Mar. PMID 9619628
    4. Multiple domains of fission yeast Cdc19p (MCM2) are required for its association with the core MCM complex. Sherman DA, et al. Mol Biol Cell, 1998 Jul. PMID 9658174, Free PMC Article
    5. A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast. Adachi Y, et al. Genes Cells, 1997 Jul. PMID 9366552

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to 3'-5' DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity NAS
    Non-traceable Author Statement
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to single-stranded DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA replication initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in double-strand break repair via break-induced replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic DNA replication initiation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in premeiotic DNA replication IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of DNA replication preinitiation complex IC
    Inferred by Curator
    more info
    		 PubMed 
    part_of MCM complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of MCM complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytosol HDA PubMed 
    part_of nuclear pre-replicative complex IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in nuclear replication fork IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    MCM complex subunit Mcm5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2815661..2820694
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356081.2 → NP_001342928.1  MCM complex subunit Mcm5 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P41389, Q9UTF5
      Conserved Domains (2) summary
      smart00350
      Location:128 → 642
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:34 → 124
      MCM_N; MCM N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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