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    pdc2 topoisomerase II-associated deadenylation-dependent mRNA-decapping factor [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540778, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pdc2
    Official Full Name
    topoisomerase II-associated deadenylation-dependent mRNA-decapping factor
    Primary source
    PomBase:SPBC19G7.10c
    Locus tag
    SPOM_SPBC19G7.10C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ppo1
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    Genomic context

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    See pdc2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003423.3 (2368835..2371613, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SUMO deconjugating enzyme Ulp1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Involvement of fission yeast Pdc2 in RNA degradation and P-body function. Wang CY, et al. RNA, 2017 Apr. PMID 28031482, Free PMC Article
    2. Cotranslational protein-RNA associations predict protein-protein interactions. Duncan CD, et al. BMC Genomics, 2014 Apr 22. PMID 24755092, Free PMC Article
    3. The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2. Jongjitwimol J, et al. PLoS One, 2014. PMID 24818994, Free PMC Article
    4. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
    5. Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome. Telekawa C, et al. Nucleic Acids Res, 2018 Nov 30. PMID 30321377, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in P-body assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in P-body IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    topoisomerase II-associated deadenylation-dependent mRNA-decapping factor

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2368835..2371613 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021884.4 → NP_595976.2  topoisomerase II-associated deadenylation-dependent mRNA-decapping factor [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595976.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O42958
      Conserved Domains (1) summary
      pfam09770
      Location:1 → 750
      PAT1; Topoisomerase II-associated protein PAT1
    Nucleotide Protein
    Heading Accession and Version

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