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    rad13 DNA repair nuclease Rad13 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541051, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rad13
    Official Full Name
    DNA repair nuclease Rad13
    Primary source
    PomBase:SPBC3E7.08c
    Locus tag
    SPOM_SPBC3E7.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See rad13 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2672990..2676569, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene vacuolar amino acid transmembrane transporter Fnx2 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Sad1-UNC-like protein Neighboring gene ncRNA Neighboring gene DNAJ domain-containing protein type Caj1/Djp1 Neighboring gene methionine aminopeptidase Fma1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Removal of cyclobutane pyrimidine dimers by the UV damage repair and nucleotide excision repair pathways of Schizosaccharomyces pombe at nucleotide resolution. Lombaerts M, et al. Nucleic Acids Res, 1999 Jul 15. PMID 10390527, Free PMC Article
    2. Contribution of base excision repair, nucleotide excision repair, and DNA recombination to alkylation resistance of the fission yeast Schizosaccharomyces pombe. Memisoglu A, et al. J Bacteriol, 2000 Apr. PMID 10735851, Free PMC Article
    3. Cross-talk between nucleotide excision and homologous recombination DNA repair pathways in the mechanism of action of antitumor trabectedin. Herrero AB, et al. Cancer Res, 2006 Aug 15. PMID 16912194
    4. An alternative eukaryotic DNA excision repair pathway. Freyer GA, et al. Mol Cell Biol, 1995 Aug. PMID 7623848, Free PMC Article
    5. Identification and characterization of the rhp23(+) DNA repair gene in Schizosaccharomyces pombe. Lombaerts M, et al. Biochem Biophys Res Commun, 2000 Feb 5. PMID 10652237

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA endonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables single-stranded DNA endodeoxyribonuclease activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in nucleotide-excision repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in nucleotide-excision repair involved in interstrand cross-link repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DNA repair nuclease Rad13

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2672990..2676569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022011.3 → NP_596095.1  DNA repair nuclease Rad13 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596095.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O59728, P28706
      Conserved Domains (3) summary
      cd09904
      Location:837 → 932
      H3TH_XPG; H3TH domain of Xeroderma pigmentosum complementation group G (XPG) nuclease, a structure-specific, divalent-metal-ion dependent, 5' nuclease
      cd09868
      Location:1 → 130
      PIN_XPG; PIN domain of Xeroderma pigmentosum complementation group G (XPG) nuclease, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
      TIGR00600
      Location:1 → 1021
      rad2; DNA excision repair protein (rad2)
    Nucleotide Protein
    Heading Accession and Version

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