U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853619, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000003915
    Locus tag
    YJR154W
    See related
    AllianceGenome:SGD:S000003915; FungiDB:YJR154W; VEuPathDB:YJR154W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable phytanoyl-CoA dioxygenase activity. Predicted to be involved in fatty acid alpha-oxidation. Located in cytoplasm. Human ortholog(s) of this gene implicated in Refsum disease; Zellweger syndrome; orofacial cleft; and peroxisomal disease. Orthologous to human PHYH (phytanoyl-CoA 2-hydroxylase). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (725784..726824)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene allantoate permease Neighboring gene endo-polygalacturonase Neighboring gene putative aryl-alcohol dehydrogenase Neighboring gene 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The reacquisition of biotin prototrophy in Saccharomyces cerevisiae involved horizontal gene transfer, gene duplication and gene clustering. Hall C, et al. Genetics, 2007 Dec. PMID 18073433, Free PMC Article
    2. Mapping Ethanol Tolerance in Budding Yeast Reveals High Genetic Variation in a Wild Isolate. Haas R, et al. Front Genet, 2019. PMID 31824552, Free PMC Article
    3. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Willingham S, et al. Science, 2003 Dec 5. PMID 14657499
    4. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. Galibert F, et al. EMBO J, 1996 May 1. PMID 8641269, Free PMC Article
    5. Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes. Fasolo J, et al. Genes Dev, 2011 Apr 1. PMID 21460040, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables phytanoyl-CoA dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in fatty acid alpha-oxidation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    NP_012688.1
    • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      725784..726824
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181812.1 → NP_012688.1  TPA: uncharacterized protein YJR154W [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012688.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWX3, P47181, Q6Q5N2
      UniProtKB/TrEMBL
      A6ZQB2, B3LQN4, C7GX80, C8ZBV4, N1P0C6
      Conserved Domains (1) summary
      COG5285
      Location:37 → 338
      PhyH; Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family [Secondary metabolites biosynthesis, transport and catabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47181.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.