ubr1 N-end-recognizing protein, UBR ubiquitin-protein ligase E3 Ubr1 [Schizosaccharomyces pombe (fission yeast)] - Gene

Summary

Official Symbol: ubr1
Official Full Name: N-end-recognizing protein, UBR ubiquitin-protein ligase E3 Ubr1
Primary source: PomBase:SPBC19C7.02
Locus tag: SPOM_SPBC19C7.02
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Schizosaccharomyces pombe (strain: 972h-)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as: SPBC32F12.14
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Chromosome II - NC_003423.3 Genomic Context describing neighboring genes

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The authors report here that Ubr1 ubiquitin ligase-dependent degradation lowered the Pap1 protein levels.[Ubr1 & Pap1]
Title: Fission yeast Ubr1 ubiquitin ligase influences the oxidative stress response via degradation of active Pap1 bZIP transcription factor in the nucleus.
Authors show that Schizosaccharomyces pombe has the N-end rule pathway in which only Ubr11, but not Ubr1, is responsible.
Title: Essential role of Ubr11, but not Ubr1, as an N-end rule ubiquitin ligase in Schizosaccharomyces pombe.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin protein ligase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables zinc ion binding	ISM Inferred from Sequence Model more info

Process	Evidence Code	Pubs
involved_in negative regulation of SREBP signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of flocculation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info
involved_in ubiquitin-dependent protein catabolic process via the N-end rule pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	NAS Non-traceable Author Statement more info
part_of ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info

Preferred Names: N-end-recognizing protein, UBR ubiquitin-protein ligase E3 Ubr1

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The following sections contain reference sequences that belong to a specific genome build. Explain