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    exo5 mitochondrial single stranded DNA specific 5'-3' exodeoxyribonuclease Exo5.2;single-strand DNA-specific 5'-3' exodeoxyribonuclease Exo5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541105, updated on 10-Oct-2024

    Summary

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    Official Symbol
    exo5
    Official Full Name
    mitochondrial single stranded DNA specific 5'-3' exodeoxyribonuclease Exo5.2;single-strand DNA-specific 5'-3' exodeoxyribonuclease Exo5
    Primary source
    PomBase:SPBC685.02
    Locus tag
    SPOM_SPBC685.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See exo5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (2772853..2774447)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene INCENP-like protein Pic1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene AP-2 adaptor complex subunit Aps2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The roles of fission yeast exonuclease 5 in nuclear and mitochondrial genome stability. Sparks JL, et al. DNA Repair (Amst), 2019 Nov. PMID 31563844, Free PMC Article
    2. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. roles of fission yeast exonuclease 5 in nuclear and mitochondrial genome stability
      Title: The roles of fission yeast exonuclease 5 in nuclear and mitochondrial genome stability.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables DNA binding IC
    Inferred by Curator
    more info
    		  
    enables single-stranded DNA 5'-3' DNA exonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables single-stranded DNA 5'-3' DNA exonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    NOT involved_in double-strand break repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in interstrand cross-link repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial DNA metabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in recombinational interstrand cross-link repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrion EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial single stranded DNA specific 5'-3' exodeoxyribonuclease Exo5.2;single-strand DNA-specific 5'-3' exodeoxyribonuclease Exo5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2772853..2774447
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022054.3 → NP_596136.1  single-strand DNA-specific 5'-3' exodeoxyribonuclease Exo5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596136.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9Y7L4
      Conserved Domains (1) summary
      pfam09810
      Location:65 → 397
      Exo5; Exonuclease V - a 5' deoxyribonuclease

    2. NM_001431024.1 → NP_001417964.1  mitochondrial single stranded DNA specific 5'-3' exodeoxyribonuclease Exo5.2 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0AAN2H839
    Nucleotide Protein
    Heading Accession and Version

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