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    Bka Bekka [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 46032, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Bkaprovided by FlyBase
    Official Full Name
    Bekkaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0010520
    Locus tag
    Dmel_CG4539
    See related
    AllianceGenome:FB:FBgn0010520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE14949; bka; CG4539; Dmel\CG4539; l(2)02695; mip
    Summary
    Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in imaginal disc; larval brain; and organism. Orthologous to human FCF1 (FCF1 rRNA-processing protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Bka in Genome Data Viewer
    Location:
    30E1-30E1; 2-37 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (9895287..9896104)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (9895287..9896104)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U snoRNA host gene 2 Neighboring gene Ribosomal protein S2 Neighboring gene Mucin 30E

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Partial inhibition of the overactivated Ku80-dependent DNA repair pathway rescues neurodegeneration in C9ORF72-ALS/FTD. Lopez-Gonzalez R, et al. Proc Natl Acad Sci U S A, 2019 May 7. PMID 31019093, Free PMC Article
    2. Altered levels of hsromega lncRNAs further enhance Ras signaling during ectopically activated Ras induced R7 differentiation in Drosophila. Ray M, et al. Gene Expr Patterns, 2019 Sep. PMID 31096022
    3. Transcriptional response to dietary restriction in Drosophila melanogaster. Ding F, et al. J Insect Physiol, 2014 Oct. PMID 24819200, Free PMC Article
    4. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. Edlich-Muth C, et al. J Mol Biol, 2015 May 22. PMID 25813344, Free PMC Article
    5. Identification of neural outgrowth genes using genome-wide RNAi. Sepp KJ, et al. PLoS Genet, 2008 Jul 4. PMID 18604272, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    bekka
    Names
    Bka-PA
    CG4539-PA
    missing imaginal precursors

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      9895287..9896104
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080128.5 → NP_524867.2  bekka [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524867.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZ77, Q9VL75
      Related
      FBpp0079470
      Conserved Domains (1) summary
      cd09864
      Location:58 → 192
      PIN_Fcf1; PIN domain of rRNA-processing protein, Fcf1 (Utp24, YDR339C), and other eukaryotic homologs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VL75 Q9VL75

    Gene LinkOut

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