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    CG3356 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37876, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3356provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034989
    Locus tag
    Dmel_CG3356
    See related
    AllianceGenome:FB:FBgn0034989
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3356
    Summary
    Enables ubiquitin conjugating enzyme binding activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is expressed in adult head and organism. Orthologous to human UBE3C (ubiquitin protein ligase E3C). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3356 in Genome Data Viewer
    Location:
    60C2-60C2; 2-106 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24197824..24202187)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20085347..20089710)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene over compensating males Neighboring gene cytosolic 5'-nucleotidase IIIB Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44827

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. UbcD4, a ubiquitin-conjugating enzyme in Drosophila melanogaster expressed in pole cells. Canning M, et al. Mol Genet Genomics, 2002 Feb. PMID 11862484
    2. Identification and characterization of a Drosophila proteasome regulatory network. Lundgren J, et al. Mol Cell Biol, 2005 Jun. PMID 15899868, Free PMC Article
    3. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Ni JQ, et al. Nat Methods, 2008 Jan. PMID 18084299, Free PMC Article
    4. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
    5. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. Blanco E, et al. BMC Dev Biol, 2010 Sep 2. PMID 20813047, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein polyubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3356-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24197824..24202187
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138052.3 → NP_611896.1  uncharacterized protein Dmel_CG3356 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611896.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W196
      Related
      FBpp0072169
      Conserved Domains (2) summary
      smart00119
      Location:788 → 1119
      HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
      cd00078
      Location:766 → 1120
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W196 Q9W196

    Gene LinkOut

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