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    CG7879 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38184, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7879provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035235
    Locus tag
    Dmel_CG7879
    See related
    AllianceGenome:FB:FBgn0035235
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg7879; Dmel\CG7879
    Summary
    Predicted to enable mRNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in schizophrenia 19. Orthologous to human RBM12 (RNA binding motif protein 12) and RBM12B (RNA binding motif protein 12B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7879 in Genome Data Viewer
    Location:
    62A5-62A6; 3-0.5 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1559813..1568608, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1559813..1568608, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Phosphocholine cytidylyltransferase 1 Neighboring gene Phosphocholine cytidylyltransferase 2 Neighboring gene uncharacterized protein Neighboring gene Peroxin 10 Neighboring gene uncharacterized protein Neighboring gene Transmembrane endosomal protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Brain Proteome of Drosophila melanogaster Is Enriched with Nuclear Proteins. Kuznetsova KG, et al. Biochemistry (Mosc), 2019 Jan. PMID 30927528
    2. Distinct regulatory programs establish widespread sex-specific alternative splicing in Drosophila melanogaster. Hartmann B, et al. RNA, 2011 Mar. PMID 21233220, Free PMC Article
    3. Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes. Housden BE, et al. PLoS Genet, 2013. PMID 23300480, Free PMC Article
    4. Identification of alternative splicing regulators by RNA interference in Drosophila. Park JW, et al. Proc Natl Acad Sci U S A, 2004 Nov 9. PMID 15492211, Free PMC Article
    5. Selection for cold resistance alters gene transcript levels in Drosophila melanogaster. Telonis-Scott M, et al. J Insect Physiol, 2009 Jun. PMID 19232407

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of alternative mRNA splicing, via spliceosome HMP PubMed 
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IC
    Inferred by Curator
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7879-PA
    CG7879-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1559813..1568608 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167896.2 → NP_728631.1  uncharacterized protein Dmel_CG7879, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728631.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T3I6, Q9W0D6
      Related
      FBpp0072707
      Conserved Domains (4) summary
      COG0724
      Location:364 → 551
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd00590
      Location:478 → 549
      RRM_SF; RNA recognition motif (RRM) superfamily
      cd12254
      Location:910 → 982
      RRM_hnRNPH_ESRPs_RBM12_like; RNA recognition motif found in heterogeneous nuclear ribonucleoprotein (hnRNP) H protein family, epithelial splicing regulatory proteins (ESRPs), Drosophila RNA-binding protein Fusilli, RNA-binding protein 12 (RBM12) and similar proteins
      cd12510
      Location:2 → 75
      RRM1_RBM12_like; RNA recognition motif 1 in RNA-binding protein RBM12, RBM12B and similar proteins

    2. NM_139369.2 → NP_647626.1  uncharacterized protein Dmel_CG7879, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647626.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T3I6, Q9W0D6
      Related
      FBpp0072706
      Conserved Domains (4) summary
      COG0724
      Location:364 → 551
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd00590
      Location:478 → 549
      RRM_SF; RNA recognition motif (RRM) superfamily
      cd12254
      Location:910 → 982
      RRM_hnRNPH_ESRPs_RBM12_like; RNA recognition motif found in heterogeneous nuclear ribonucleoprotein (hnRNP) H protein family, epithelial splicing regulatory proteins (ESRPs), Drosophila RNA-binding protein Fusilli, RNA-binding protein 12 (RBM12) and similar proteins
      cd12510
      Location:2 → 75
      RRM1_RBM12_like; RNA recognition motif 1 in RNA-binding protein RBM12, RBM12B and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T3I6 Q8T3I6
    Q9W0D6 Q9W0D6

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