U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    LTV1 LTV1 ribosome biogenesis factor [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36146, updated on 9-Dec-2024

    Summary

    Official Symbol
    LTV1provided by FlyBase
    Official Full Name
    LTV1 ribosome biogenesis factorprovided by FlyBase
    Primary source
    FLYBASE:FBgn0027525
    Locus tag
    Dmel_CG7686
    See related
    AllianceGenome:FB:FBgn0027525
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD21529; CG7686; Dmel\CG7686
    Summary
    Enables ribosome binding activity. Involved in rRNA processing; ribosomal small subunit biogenesis; and ribosomal small subunit export from nucleus. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol and nucleus. Is expressed in organism. Human ortholog(s) of this gene implicated in inflammatory poikiloderma with hair abnormalities and acral keratoses. Orthologous to human LTV1 (LTV1 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See LTV1 in Genome Data Viewer
    Location:
    47C3-47C3; 2-63 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10836570..10838727, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6724075..6726232, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene alkaliphile Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45136 Neighboring gene long non-coding RNA:CR44302

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ribosome binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in rRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in ribosomal small subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal small subunit biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal small subunit biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in ribosomal small subunit export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal small subunit export from nucleus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of preribosome, small subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    LTV1 ribosome biogenesis factor
    Names
    CG7686-PA
    CG7686-PB
    LTV1-PA
    LTV1-PB
    Low temperature viability protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10836570..10838727 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299371.1NP_001286300.1  LTV1 ribosome biogenesis factor, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286300.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0B4LF59, Q7KN79
      Conserved Domains (1) summary
      pfam04180
      Location:10462
      LTV; Low temperature viability protein
    2. NM_136776.4NP_610620.1  LTV1 ribosome biogenesis factor, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610620.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0B4LF59, Q7KN79
      Related
      FBpp0087340
      Conserved Domains (1) summary
      pfam04180
      Location:10462
      LTV; Low temperature viability protein