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    Xlr4c X-linked lymphocyte-regulated 4C [ Mus musculus (house mouse) ]

    Gene ID: 72891, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Xlr4cprovided by MGI
    Official Full Name
    X-linked lymphocyte-regulated 4Cprovided by MGI
    Primary source
    MGI:MGI:3574099
    See related
    Ensembl:ENSMUSG00000031362 AllianceGenome:MGI:3574099
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2900036K24Rik
    Summary
    Predicted to be involved in meiotic cell cycle and spermatid development. Predicted to be active in synaptonemal complex. Is expressed in several structures, including brain; hemolymphoid system; hindgut diverticulum; placenta; and yolk sac. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in placenta adult (RPKM 19.1) and thymus adult (RPKM 3.6) See more
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    Genomic context

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    See Xlr4c in Genome Data Viewer
    Location:
    X A7.3; X 37.29 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (72277682..72286736, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (73234076..73243130, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene X-linked lymphocyte-regulated 4B Neighboring gene factor 8-associated gene A Neighboring gene X-linked lymphocyte-regulated 3C Neighboring gene STARR-seq mESC enhancer starr_47345 Neighboring gene X-linked lymphocyte-regulated 5C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. At Term, XmO and XpO Mouse Placentas Show Differences in Glucose Metabolism in the Trophectoderm-Derived Outer Zone. He N, et al. Front Cell Dev Biol, 2017. PMID 28680878, Free PMC Article
    2. Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice. Davies W, et al. Nat Genet, 2005 Jun. PMID 15908950
    3. Identification of a cluster of X-linked imprinted genes in mice. Raefski AS, et al. Nat Genet, 2005 Jun. PMID 15908953
    4. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Tamplin OJ, et al. Dev Biol, 2011 Dec 15. PMID 22008794
    5. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spermatid development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in synaptonemal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    X-linked lymphocyte-regulated 4C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183094.3 → NP_898917.2  X-linked lymphocyte-regulated 4C

      See identical proteins and their annotated locations for NP_898917.2

      Status: VALIDATED

      Source sequence(s)
      AA190046, AK166871
      Consensus CDS
      CCDS41012.1
      UniProtKB/TrEMBL
      Q3TKR2, Q9JJQ8
      Related
      ENSMUSP00000110176.2, ENSMUST00000114530.8
      Conserved Domains (1) summary
      pfam04803
      Location:60 → 188
      Cor1; Cor1/Xlr/Xmr conserved region

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      72277682..72286736 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251507.2 → XP_030107367.1  X-linked lymphocyte-regulated 4C isoform X1

      UniProtKB/TrEMBL
      Q3TKR2, Q9JJQ8
      Related
      ENSMUSP00000070117.3, ENSMUST00000068551.9
      Conserved Domains (1) summary
      pfam04803
      Location:60 → 188
      Cor1; Cor1/Xlr/Xmr conserved region

    2. XM_030251506.1 → XP_030107366.1  X-linked lymphocyte-regulated 4C isoform X1

      UniProtKB/TrEMBL
      Q3TKR2, Q9JJQ8
      Conserved Domains (1) summary
      pfam04803
      Location:60 → 188
      Cor1; Cor1/Xlr/Xmr conserved region
    Nucleotide Protein Strain
    Heading Accession and Version

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