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    ASA1 Asa1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856200, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ASA1
    Official Full Name
    Asa1p
    Primary source
    SGD:S000006289
    Locus tag
    YPR085C
    See related
    AllianceGenome:SGD:S000006289; FungiDB:YPR085C; VEuPathDB:YPR085C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in chromatin organization. Part of TTT Hsp90 cochaperone complex. Orthologous to human GNB1L (G protein subunit beta 1 like). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ASA1 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (708497..709828, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Mdm36p Neighboring gene uncharacterized protein Neighboring gene transcription factor SUA7 Neighboring gene RNA-binding signal recognition particle subunit SRP54

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Saccharomyces cerevisiae Tel2 plays roles in TORC signaling and telomere maintenance that can be mutationally separated. Rozario D, et al. Biochem Biophys Res Commun, 2012 Jan 27. PMID 22227188
    2. Two separate pathways regulate protein stability of ATM/ATR-related protein kinases Mec1 and Tel1 in budding yeast. Goto GH, et al. PLoS Genet, 2017 Aug. PMID 28827813, Free PMC Article
    3. Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Shevchenko A, et al. Genome Biol, 2008. PMID 19040720, Free PMC Article
    4. Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast. Au WC, et al. PLoS Genet, 2020 Feb. PMID 32032354, Free PMC Article
    5. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of TTT Hsp90 cochaperone complex HDA PubMed 
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Asa1p
    NP_015410.2
    • Subunit of the TTT complex and regulator of telomere length; subunit of the TTT Hsp90 cochaperone complex that is involved in chromatin remodeling and telomeric chromatin regulation; telomere length regulator involved in the stability or biogenesis of PIKKs such as TORC1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      708497..709828 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184182.1 → NP_015410.2  TPA: Asa1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015410.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZWX0, B3LK55, C8ZJB0, D6W487, Q06822
      UniProtKB/TrEMBL
      G2WPQ5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06822.2

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