HXT15 hexose transporter HXT15 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: HXT15
Official Full Name: hexose transporter HXT15
Primary source: SGD:S000002404
Locus tag: YDL245C
See related: AllianceGenome:SGD:S000002404; FungiDB:YDL245C; VEuPathDB:YDL245C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: HLT2
Summary: Enables D-glucose transmembrane transporter activity; fructose transmembrane transporter activity; and mannose transmembrane transporter activity. Involved in carbohydrate transmembrane transport. Located in cell periphery. Orthologous to human SLC2A6 (solute carrier family 2 member 6) and SLC2A8 (solute carrier family 2 member 8). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome IV - NC_001136.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables D-glucose transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables carbohydrate:proton symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables fructose transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables mannose transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in carbohydrate transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in fructose transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in hexose transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mannitol transmembrane transport	IGI Inferred from Genetic Interaction more info	PubMed
involved_in mannose transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in sorbitol transmembrane transport	IGI Inferred from Genetic Interaction more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in xylitol transmembrane transport	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in cell periphery	HDA more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

NP_010036.1

Putative transmembrane polyol transporter; supports growth on and uptake of mannitol, sorbitol and xylitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; similarity to hexose transporters; expression is induced by low levels of glucose and repressed by high levels of glucose

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The following sections contain reference sequences that belong to a specific genome build. Explain