Ankrd13d ankyrin repeat domain 13 family, member D [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ankrd13dprovided by MGI
Official Full Name: ankyrin repeat domain 13 family, member Dprovided by MGI
Primary source: MGI:MGI:1915673
See related: Ensembl:ENSMUSG00000005986 AllianceGenome:MGI:1915673
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 0710001P18Rik
Summary: Predicted to enable ubiquitin-modified protein reader activity. Predicted to be involved in negative regulation of receptor internalization. Predicted to be located in perinuclear region of cytoplasm and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human ANKRD13D (ankyrin repeat domain 13D). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in CNS E18 (RPKM 27.3), cortex adult (RPKM 20.7) and 18 other tissues See more
Orthologs: human all
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Genomic context

Location:: 19 A; 19 3.96 cM

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	19	NC_000085.7 (4320208..4333165, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	19	NC_000085.6 (4270180..4284053, complement)

Chromosome 19 - NC_000085.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ubiquitin-modified protein reader activity	ISO Inferred from Sequence Orthology more info
enables ubiquitin-modified protein reader activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in negative regulation of receptor internalization	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of receptor internalization	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in late endosome	IEA Inferred from Electronic Annotation more info
located_in perinuclear region of cytoplasm	ISO Inferred from Sequence Orthology more info
located_in perinuclear region of cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: ankyrin repeat domain-containing protein 13D

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_026720.2 → NP_080996.2 ankyrin repeat domain-containing protein 13D

See identical proteins and their annotated locations for NP_080996.2

Status: VALIDATED

Source sequence(s)

AK155698, BC058982

Consensus CDS

CCDS50351.1

UniProtKB/Swiss-Prot

G3X9A8, Q6PD24

Related

ENSMUSP00000053783.7, ENSMUST00000056888.13

Conserved Domains (5) summary

cd00204
Location:9 → 97

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam11904
Location:155 → 469

GPCR_chapero_1; GPCR-chaperone

pfam12796
Location:9 → 66

Ank_2; Ankyrin repeats (3 copies)

pfam13637
Location:40 → 93

Ank_4; Ankyrin repeats (many copies)

sd00045
Location:39 → 70

ANK; ANK repeat [structural motif]