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    RPS27B ribosomal 40S subunit protein S27B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856415, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPS27B
    Official Full Name
    ribosomal 40S subunit protein S27B
    Primary source
    SGD:S000001063
    Locus tag
    YHR021C
    See related
    AllianceGenome:SGD:S000001063; FungiDB:YHR021C; VEuPathDB:YHR021C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    A structural constituent of ribosome. Involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 17. Orthologous to human RPS27 (ribosomal protein S27) and RPS27L (ribosomal protein S27 like). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPS27B in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    2
    Sequence:
    Chromosome: VIII; NC_001140.6 (147871..148669, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene proline--tRNA ligase Neighboring gene tRNA-Ala Neighboring gene Ecm12p Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of Rrp7p, an essential yeast protein involved in pre-rRNA processing and ribosome assembly. Baudin-Baillieu A, et al. Mol Cell Biol, 1997 Sep. PMID 9271380, Free PMC Article
    2. Genetic and biochemical characterization of antisuppressor mutants in the yeast Saccharomyces cerevisiae. Ishiguro J. Curr Genet, 1981 Dec. PMID 24185993
    3. Genome-wide binding map of the histone deacetylase Rpd3 in yeast. Kurdistani SK, et al. Nat Genet, 2002 Jul. PMID 12089521
    4. The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan. Mittal N, et al. Nat Commun, 2017 Sep 6. PMID 28878244, Free PMC Article
    5. Protein topography of the 40 S ribosomal subunit from Saccharomyces cerevisiae as shown by chemical cross-linking. Yeh YC, et al. J Biol Chem, 1986 Oct 25. PMID 3533916

    See all (78) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ribosomal small subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal small subunit assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S27B
    NP_011885.1
    • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S27, no bacterial homolog; RPS27B has a paralog, RPS27A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      147871..148669 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179151.1 → NP_011885.1  TPA: ribosomal 40S subunit protein S27B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011885.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKW6, P38711
      UniProtKB/TrEMBL
      A6ZSS5, C8ZA88, G2WF90
      Conserved Domains (1) summary
      PTZ00083
      Location:5 → 82
      PTZ00083; 40S ribosomal protein S27; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38711.1

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