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    Tmem177 transmembrane protein 177 [ Mus musculus (house mouse) ]

    Gene ID: 66343, updated on 27-Dec-2024

    Summary

    Official Symbol
    Tmem177provided by MGI
    Official Full Name
    transmembrane protein 177provided by MGI
    Primary source
    MGI:MGI:1913593
    See related
    Ensembl:ENSMUSG00000036975 AllianceGenome:MGI:1913593
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2300008B03Rik
    Summary
    Predicted to be involved in mitochondrial respiratory chain complex II assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be active in membrane. Is expressed in cerebral cortex; cerebral cortex intermediate zone; cerebral cortex subventricular zone; and cerebral cortex ventricular layer. Orthologous to human TMEM177 (transmembrane protein 177). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 6.3), heart adult (RPKM 3.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Tmem177 in Genome Data Viewer
    Location:
    1 E2.3; 1 52.53 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (119835620..119840913, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (119907890..119913183, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene 29658 Neighboring gene predicted gene 3551 Neighboring gene predicted gene 28209 Neighboring gene STARR-positive B cell enhancer ABC_E9474 Neighboring gene cilia and flagella associated protein 221 Neighboring gene predicted gene, 17973 Neighboring gene predicted gene, 33817

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in mitochondrial respiratory chain complex II assembly IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175106.4NP_780315.1  transmembrane protein 177

      See identical proteins and their annotated locations for NP_780315.1

      Status: VALIDATED

      Source sequence(s)
      BB578893, BC094344
      Consensus CDS
      CCDS15228.1
      UniProtKB/Swiss-Prot
      Q8BPE4
      Related
      ENSMUSP00000042416.6, ENSMUST00000037906.6

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      119835620..119840913 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)