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    SMA2 Sma2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854936, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SMA2
    Official Full Name
    Sma2p
    Primary source
    SGD:S000004531
    Locus tag
    YML066C
    See related
    AllianceGenome:SGD:S000004531; FungiDB:YML066C; VEuPathDB:YML066C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in spore membrane bending pathway. Located in cytoplasm and prospore membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SMA2 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (140424..141533, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene RBR-type E3 ubiquitin transferase Neighboring gene Erv41p Neighboring gene origin recognition complex subunit 1 Neighboring gene Ras family GTPase TEM1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Dysferlin Domain-Only Protein, Spo73, Is Required for Prospore Membrane Extension in Saccharomyces cerevisiae. Okumura Y, et al. mSphere, 2016 Jan-Feb. PMID 27303688, Free PMC Article
    2. Erv14 family cargo receptors are necessary for ER exit during sporulation in Saccharomyces cerevisiae. Nakanishi H, et al. J Cell Sci, 2007 Mar 1. PMID 17298976
    3. The SpoMBe pathway drives membrane bending necessary for cytokinesis and spore formation in yeast meiosis. Maier P, et al. EMBO J, 2008 Sep 17. PMID 18756268, Free PMC Article
    4. Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae. Deutschbauer AM, et al. Proc Natl Acad Sci U S A, 2002 Nov 26. PMID 12432101, Free PMC Article
    5. A screen for genes required for meiosis and spore formation based on whole-genome expression. Rabitsch KP, et al. Curr Biol, 2001 Jul 10. PMID 11470404

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the SpoMBe pathway of Sma2p and Spo1p involves asymmetric distribution of Sma2p and does not involve a GPI-protein-containing matrix
      Title: The SpoMBe pathway drives membrane bending necessary for cytokinesis and spore formation in yeast meiosis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore-type prospore membrane formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spore membrane bending pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type vacuole HDA PubMed 
    located_in fungal-type vacuole membrane HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in prospore membrane HDA PubMed 
    located_in prospore membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in prospore membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Sma2p
    NP_013645.1
    • Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      140424..141533 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182425.1 → NP_013645.1  TPA: Sma2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013645.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZLZ9, D6VZA7, Q04658
      UniProtKB/TrEMBL
      B3LLI9, C8ZED9, G2WJY9, N1P0U6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04658.1

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