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    Fv1 Friend virus susceptibility 1 [ Mus musculus (house mouse) ]

    Gene ID: 14349, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fv1provided by MGI
    Official Full Name
    Friend virus susceptibility 1provided by MGI
    Primary source
    MGI:MGI:95595
    See related
    Ensembl:ENSMUSG00000070583 AllianceGenome:MGI:95595
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rv1; Fv-1; Fv1d; Rv-1
    Summary
    Acts upstream of or within response to virus. Located in Golgi apparatus. Is expressed in several structures, including endocrine gland; ganglia; nasal cavity epithelium; submandibular gland primordium; and thymus primordium. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Fv1 in Genome Data Viewer
    Location:
    4 E1; 4 78.56 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (147953436..147954815)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (147868979..147870358)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S19, pseudogene 3 Neighboring gene zinc finger protein 933 Neighboring gene STARR-positive B cell enhancer ABC_E4726 Neighboring gene STARR-positive B cell enhancer ABC_E181 Neighboring gene migration and invasion inhibitory protein Neighboring gene mitofusin 2 Neighboring gene STARR-positive B cell enhancer ABC_E9625 Neighboring gene procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to virus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within response to virus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    Friend virus susceptibility protein 1
    Names
    Fv1 gammaretrovirus restriction factor
    Fv1 restriction factor
    Rauscher leukemia virus susceptibility 1
    retrovirus restriction protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010244.3NP_034374.2  Friend virus susceptibility protein 1

      See identical proteins and their annotated locations for NP_034374.2

      Status: VALIDATED

      Source sequence(s)
      X97719
      Consensus CDS
      CCDS38964.1
      UniProtKB/Swiss-Prot
      P70213, P70214
      UniProtKB/TrEMBL
      X2FIS1, X2FP38
      Related
      ENSMUSP00000092054.2, ENSMUST00000094481.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      147953436..147954815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)