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    lepA translation elongation factor 4 [ Cereibacter sphaeroides 2.4.1 ]

    Gene ID: 3719522, updated on 26-Dec-2024

    Summary

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    Gene symbol
    lepA
    Gene description
    translation elongation factor 4
    Locus tag
    RSP_RS03455
    Gene type
    protein coding
    Organism
    Cereibacter sphaeroides 2.4.1 (strain: 2.4.1, culture-collection: ATCC:BAA-808, type-material: type strain of Rhodobacter sphaeroides)
    Lineage
    Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria; Rhodobacterales; Paracoccaceae; Cereibacter
    Old locus tag
    RSP_2088
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    Genomic context

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    Location:
    chromosome: 1
    Sequence:
    Chromosome: 1; NC_007493.2 (681637..683436, complement)

    Chromosome 1 - NC_007493.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene entericidin A/B family lipoprotein Neighboring gene tRNA-Gly Neighboring gene pyruvate carboxylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_007493.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EF4 reveals the energy barrier for tRNA back-translocation in the peptidyl transferase center. Song G, et al. RNA Biol, 2016 Oct 2. PMID 27472653, Free PMC Article
    2. Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome. Kumar V, et al. J Biol Chem, 2016 Jun 17. PMID 27137929, Free PMC Article
    3. The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis. Liu H, et al. Proc Natl Acad Sci U S A, 2011 Sep 27. PMID 21930951, Free PMC Article
    4. Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome. Gibbs MR, et al. Proc Natl Acad Sci U S A, 2017 Jan 31. PMID 28096346, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    translation elongation factor 4
    WP_011337228.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_007493.2 Reference assembly

      Range
      681637..683436 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_011337228.1 translation elongation factor 4 [Cereibacter sphaeroides]

      UniProtKB/Swiss-Prot
      Q3J4P0
      UniProtKB/TrEMBL
      A0AAX1UI27