U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ATG45 Atg45p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854788, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ATG45
    Official Full Name
    Atg45p
    Primary source
    SGD:S000001286
    Locus tag
    YIL024C
    See related
    AllianceGenome:SGD:S000001286; FungiDB:YIL024C; VEuPathDB:YIL024C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables glycogen binding activity. Involved in ascospore formation; cellular response to nitrogen starvation; and glycophagy. Is active in autophagosome and cytosol. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ATG45 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (308602..309171, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Emc5p Neighboring gene Irr1p Neighboring gene Zn(2+) transporter YKE4 Neighboring gene protein translocase subunit TIM44

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The Ume6 regulon coordinates metabolic and meiotic gene expression in yeast. Williams RM, et al. Proc Natl Acad Sci U S A, 2002 Oct 15. PMID 12370439, Free PMC Article
    2. Chemogenomic Study of Carboplatin in Saccharomyces cerevisiae: Inhibition of the NEDDylation Process Overcomes Cellular Resistance Mediated by HuR and Cullin Proteins. de Sousa GF, et al. PLoS One, 2015. PMID 26692264, Free PMC Article
    3. A meiotic XPF-ERCC1-like complex recognizes joint molecule recombination intermediates to promote crossover formation. De Muyt A, et al. Genes Dev, 2018 Feb 1. PMID 29440262, Free PMC Article
    4. Selective defects in gene expression control genome instability in yeast splicing mutants. Tam AS, et al. Mol Biol Cell, 2019 Jan 15. PMID 30462576, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome IX. Churcher C, et al. Nature, 1997 May 29. PMID 9169870

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    General protein information

    Go to the top of the page Help
    Preferred Names
    Atg45p
    NP_012240.3
    • Autophagy receptor for glycogen; cytosolic receptor for glycogen that mediates glycophagy, the autophagy of glycogen; induced during prolonged nitrogen starvation and highly expressed during sporulation, both glycophagy-inducing conditions; expression directly regulated by Ume6p, a metabolic and meiotic transcriptional regulator; contains a glycogen-binding domain (GBD) and an Atg8 family-interacting motif (AIM) proposed to facilitate sequestration of glycogen by autophagic isolation membranes

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      308602..309171 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179374.3 → NP_012240.3  TPA: Atg45p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012240.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVQ5, P40543
      UniProtKB/TrEMBL
      A6ZVP3, B3LTN2, C7GPX2, C8ZAM4, G2WGC0, N1P958
      Conserved Domains (1) summary
      cd02859
      Location:19 → 92
      E_set_AMPKbeta_like_N; N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40543.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools