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    CBP1 Cbp1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853221, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CBP1
    Official Full Name
    Cbp1p
    Primary source
    SGD:S000003745
    Locus tag
    YJL209W
    See related
    AllianceGenome:SGD:S000003745; FungiDB:YJL209W; VEuPathDB:YJL209W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables mRNA binding activity. Involved in aerobic respiration and mitochondrial mRNA catabolic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See CBP1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (38005..39969)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene oligopeptide transporter OPT1 Neighboring gene ubiquitin-protein ligase peroxin 2 Neighboring gene ribonuclease Neighboring gene Laa1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast CBP1 mRNA 3' end formation is regulated during the induction of mitochondrial function. Mayer SA, et al. Mol Cell Biol, 1991 Feb. PMID 1990285, Free PMC Article
    2. Identification of the CBP1 polypeptide in mitochondrial extracts from Saccharomyces cerevisiae. Weber ER, et al. J Biol Chem, 1990 Jan 25. PMID 2104848
    3. CBP1 function is required for stability of a hybrid cob-oli1 transcript in yeast mitochondria. Mittelmeier TM, et al. Curr Genet, 1990 Dec. PMID 2150347
    4. The yeast CBP1 gene produces two differentially regulated transcripts by alternative 3'-end formation. Mayer SA, et al. Mol Cell Biol, 1989 Oct. PMID 2573826, Free PMC Article
    5. Assembly of the mitochondrial membrane system. Nucleotide sequence of a yeast nuclear gene (CBP1) involved in 5' end processing of cytochrome b pre-mRNA. Dieckmann CL, et al. J Biol Chem, 1984 Apr 25. PMID 6325407

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mitochondrial localization of the splicing endonuclease complex is required for the cleavage of the CBP1 mRNA.
      Title: The tRNA Splicing Endonuclease Complex Cleaves the Mitochondria-localized CBP1 mRNA.
    2. Data suggests that Cbp1 is loosely associated with the mitochondrial membrane through weak hydrophobic interactions and it is part of a single 900,000-Da complex. .
      Title: The mitochondrial message-specific mRNA protectors Cbp1 and Pet309 are associated in a high-molecular weight complex.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in aerobic respiration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial mRNA catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Cbp1p
    NP_012326.1
    • Mitochondrial protein, regulator of COB mRNA stability and translation; interacts with the 5'-untranslated region of the COB mRNA; found in a complex at the inner membrane along with Pet309p; localizes to mitochondrial foci upon DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      38005..39969
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181642.1 → NP_012326.1  TPA: Cbp1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012326.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVY5, P07252
      UniProtKB/TrEMBL
      N1P174
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P07252.1

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