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    VLD1 Vld1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854831, updated on 9-Dec-2024

    Summary

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    Official Symbol
    VLD1
    Official Full Name
    Vld1p
    Primary source
    SGD:S000001453
    Locus tag
    YIR014W
    See related
    AllianceGenome:SGD:S000001453; FungiDB:YIR014W; VEuPathDB:YIR014W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in endoplasmic reticulum and fungal-type vacuole. Part of Dsc E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See VLD1 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (381086..381814)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Sqt1p Neighboring gene Gat4p Neighboring gene ribonuclease P protein subunit RPR2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ubiquitination of phosphatidylethanolamine in organellar membranes. Sakamaki JI, et al. Mol Cell, 2022 Oct 6. PMID 36044902
    2. The Ume6 regulon coordinates metabolic and meiotic gene expression in yeast. Williams RM, et al. Proc Natl Acad Sci U S A, 2002 Oct 15. PMID 12370439, Free PMC Article
    3. Sorting of a multi-subunit ubiquitin ligase complex in the endolysosome system. Yang X, et al. Elife, 2018 Jan 22. PMID 29355480, Free PMC Article
    4. A split-ubiquitin two-hybrid screen for proteins physically interacting with the yeast amino acid transceptor Gap1 and ammonium transceptor Mep2. Van Zeebroeck G, et al. PLoS One, 2011. PMID 21912684, Free PMC Article
    5. The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis. Yap WS, et al. J Cell Sci, 2020 Nov 5. PMID 33033181, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of Dsc E3 ubiquitin ligase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in fungal-type vacuole HDA PubMed 
    located_in fungal-type vacuole membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuolar membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Vld1p
    NP_012279.4
    • Component of Dsc E3 ligase complex in vacuolar membranes; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; YIR014W is a non-essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      381086..381814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179536.3 → NP_012279.4  TPA: Vld1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012279.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVU4, P40570
      UniProtKB/TrEMBL
      A6ZVT3, B3LTJ5, C7GJF8, N1P0R1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40570.2

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