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    PEX11 Pex11p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854018, updated on 27-Dec-2024

    Summary

    Official Symbol
    PEX11
    Official Full Name
    Pex11p
    Primary source
    SGD:S000005507
    Locus tag
    YOL147C
    See related
    AllianceGenome:SGD:S000005507; FungiDB:YOL147C; VEuPathDB:YOL147C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    PMP24; PMP27
    Summary
    Involved in medium-chain fatty acid transport and peroxisome fission. Located in endoplasmic reticulum and peroxisomal membrane. Part of peroxisomal importomer complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 14B. Orthologous to several human genes including PEX11A (peroxisomal biogenesis factor 11 alpha). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See PEX11 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (47933..48643, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Dcp1p Neighboring gene Spt20p Neighboring gene DNA replication protein PSF3 Neighboring gene Ctr9p

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in medium-chain fatty acid transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in peroxisome fission IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in peroxisome fission IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peroxisome fission IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in peroxisome organization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of peroxisomal importomer complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in peroxisomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in peroxisomal membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Pex11p
    NP_014494.1
    • Peroxisomal protein required for medium-chain fatty acid oxidation; also required for peroxisome proliferation, possibly by inducing membrane curvature; localization regulated by phosphorylation; transcription regulated by Adr1p and Pip2p-Oaf1p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      47933..48643 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183401.1NP_014494.1  TPA: Pex11p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014494.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1S2, Q12462
      UniProtKB/TrEMBL
      A6ZN65, B3LIS0, B5VRB5, C7GV22, C8ZHH0, G2WM91, N1NVQ5
      Conserved Domains (1) summary
      pfam05648
      Location:12233
      PEX11; Peroxisomal biogenesis factor 11 (PEX11)