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    Zfp316 zinc finger protein 316 [ Mus musculus (house mouse) ]

    Gene ID: 54201, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp316provided by MGI
    Official Full Name
    zinc finger protein 316provided by MGI
    Primary source
    MGI:MGI:1860402
    See related
    Ensembl:ENSMUSG00000046658 AllianceGenome:MGI:1860402
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mzf3; Emzf1; Znf316
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in genitourinary system. Orthologous to human ZNF316 (zinc finger protein 316). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 8.9), adrenal adult (RPKM 7.2) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp316 in Genome Data Viewer
    Location:
    5 G2; 5 82.03 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (143235450..143258269, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (143249695..143270031, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930448H16 gene Neighboring gene predicted gene, 38735 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:143996641-143996853 Neighboring gene zinc finger protein 12 Neighboring gene cDNA sequence BC030343 Neighboring gene zinc finger protein 853 Neighboring gene predicted gene, 52794

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population. Mugford JW, et al. Dev Biol, 2009 Sep 15. PMID 19591821, Free PMC Article
    2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    3. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 316
    Names
    kruppel-related zinc finger protein
    transcription factor MZF-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_017467.3 → NP_059495.3  zinc finger protein 316

      See identical proteins and their annotated locations for NP_059495.3

      Status: VALIDATED

      Source sequence(s)
      AC123686, BC057078
      Consensus CDS
      CCDS19838.2
      UniProtKB/Swiss-Prot
      Q6PGE4
      UniProtKB/TrEMBL
      G3XA34
      Related
      ENSMUSP00000125416.2, ENSMUST00000161448.8
      Conserved Domains (6) summary
      smart00349
      Location:155 → 215
      KRAB; krueppel associated box
      COG5048
      Location:763 → 950
      COG5048; FOG: Zn-finger [General function prediction only]
      PRK13108
      Location:507 → 584
      PRK13108; prolipoprotein diacylglyceryl transferase; Reviewed
      sd00017
      Location:850 → 870
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:710 → 730
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:383 → 408
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      143235450..143258269 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504718.5 → XP_006504781.1  zinc finger protein 316 isoform X1

      See identical proteins and their annotated locations for XP_006504781.1

      UniProtKB/Swiss-Prot
      Q6PGE4
      UniProtKB/TrEMBL
      G3XA34
      Conserved Domains (6) summary
      smart00349
      Location:155 → 215
      KRAB; krueppel associated box
      COG5048
      Location:763 → 950
      COG5048; FOG: Zn-finger [General function prediction only]
      PRK13108
      Location:507 → 584
      PRK13108; prolipoprotein diacylglyceryl transferase; Reviewed
      sd00017
      Location:850 → 870
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:710 → 730
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:383 → 408
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PGE4.1 GenPept UniProtKB/Swiss-Prot:Q6PGE4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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