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    Snx22 sorting nexin 22 [ Mus musculus (house mouse) ]

    Gene ID: 382083, updated on 27-Nov-2024

    Summary

    Official Symbol
    Snx22provided by MGI
    Official Full Name
    sorting nexin 22provided by MGI
    Primary source
    MGI:MGI:2685966
    See related
    Ensembl:ENSMUSG00000039452 AllianceGenome:MGI:2685966
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1120
    Summary
    Predicted to enable phosphatidylinositol phosphate binding activity. Is expressed in several structures, including gut; liver; lung; male reproductive gland or organ; and sensory organ. Orthologous to human SNX22 (sorting nexin 22). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 80.2), liver E18 (RPKM 56.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Snx22 in Genome Data Viewer
    Location:
    9 C; 9 35.69 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (65972456..65977041, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (66065174..66069759, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene thyroid hormone receptor interactor 4 Neighboring gene STARR-seq mESC enhancer starr_24473 Neighboring gene PCNA clamp associated factor Neighboring gene predicted gene, 23248 Neighboring gene casein kinase 1, gamma 1 Neighboring gene predicted gene, 22657 Neighboring gene STARR-positive B cell enhancer mm9_chr9:65852147-65852448 Neighboring gene STARR-positive B cell enhancer ABC_E6757 Neighboring gene STARR-positive B cell enhancer ABC_E11412 Neighboring gene STARR-seq mESC enhancer starr_24475 Neighboring gene peptidylprolyl isomerase B Neighboring gene sorting nexin 1 Neighboring gene STARR-positive B cell enhancer ABC_E5080 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:65974328-65974632 Neighboring gene cytosolic iron-sulfur assembly component 2A

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables phosphatidylinositol phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025612.2NP_001020783.1  sorting nexin-22 isoform 1

      See identical proteins and their annotated locations for NP_001020783.1

      Status: VALIDATED

      Source sequence(s)
      AC112676
      Consensus CDS
      CCDS40671.1
      UniProtKB/TrEMBL
      Q8C084
      Related
      ENSMUSP00000044389.6, ENSMUST00000044711.7
      Conserved Domains (1) summary
      cd06880
      Location:2115
      PX_SNX22; The phosphoinositide binding Phox Homology domain of Sorting Nexin 22
    2. NM_001379335.1NP_001366264.1  sorting nexin-22 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC112676
      Conserved Domains (1) summary
      cd06880
      Location:2115
      PX_SNX22; The phosphoinositide binding Phox Homology domain of Sorting Nexin 22
    3. NM_001379336.1NP_001366265.1  sorting nexin-22 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC112676
      Conserved Domains (1) summary
      cl02563
      Location:280
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      65972456..65977041 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)