U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mxd4.S MAX dimerization protein 4 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 403397, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    mxd4.S
    Official Full Name
    MAX dimerization protein 4 S homeolog
    Primary source
    Xenbase:XB-GENE-6256011
    Locus tag
    XELAEV_18008877mg
    See related
    EnsemblRapid:ENSXLAG00005025589 AllianceGenome:Xenbase:XB-GENE-6256011
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    mad4; xmad4; mst149; mxd4-a; mxd4-b; bhlhc12; mstp149
    Summary
    Predicted to enable protein dimerization activity. Predicted to be located in nucleus. Is expressed in ectoderm; liver and biliary system; mesoderm; and urinary system. Orthologous to human MXD4 (MAX dimerization protein 4). [provided by Alliance of Genome Resources, Jan 2025]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mxd4.S in Genome Data Viewer
    Location:
    chromosome: 1S
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (12785054..12832457, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (12649489..12697564, complement)

    Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase 8 like S homeolog Neighboring gene HAUS augmin-like complex subunit 3 Neighboring gene zinc finger FYVE-type containing 28a S homeolog Neighboring gene uncharacterized LOC121399266

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC84841

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    MAX dimerization protein 4 S homeolog
    Names
    basic helix-loop-helix transcription factor XMad4-236

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001090987.1 → NP_001084456.1  MAX dimerization protein 4 S homeolog

      See identical proteins and their annotated locations for NP_001084456.1

      Status: PROVISIONAL

      Source sequence(s)
      AF127040
      UniProtKB/TrEMBL
      A0A974I2Z8, Q9W6H2
      Related
      ENSXLAP00005076227.1, ENSXLAT00005077810.1
      Conserved Domains (1) summary
      smart00353
      Location:92 → 144
      HLH; helix loop helix domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      12785054..12832457 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018235426.2 → XP_018090915.1  MAX dimerization protein 4 S homeolog isoform X2

      UniProtKB/TrEMBL
      A0A974I2Z8, Q5HZZ5
      Related
      ENSXLAP00005076290.1, ENSXLAT00005077881.1

    2. XM_018235417.2 → XP_018090906.1  MAX dimerization protein 4 S homeolog isoform X1

      UniProtKB/TrEMBL
      A0A1L8HKS2, A0A974DTB8, A0A974I2Z8

    3. XM_041574538.1 → XP_041430472.1  MAX dimerization protein 4 S homeolog isoform X3

      UniProtKB/TrEMBL
      A0A8J1LLT0, Q561K6
      Related
      ENSXLAP00005076078.1, ENSXLAT00005077654.1
      Conserved Domains (1) summary
      cd18929
      Location:16 → 103
      bHLHzip_Mad4; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-associated protein 4 (Mad4) and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials