U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    leo1.S LEO1 homolog, Paf1/RNA polymerase II complex component S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 443607, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    leo1.S
    Official Full Name
    LEO1 homolog, Paf1/RNA polymerase II complex component S homeolog
    Primary source
    Xenbase:XB-GENE-5828312
    Locus tag
    XELAEV_18020633mg
    See related
    EnsemblRapid:ENSXLAG00005005325 AllianceGenome:Xenbase:XB-GENE-5828312
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    leo1
    Summary
    Predicted to act upstream of or within transcription elongation by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Cdc73/Paf1 complex. Orthologous to human LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Jan 2025]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See leo1.S in Genome Data Viewer
    Location:
    chromosome: 3S
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3S NC_054376.1 (51980791..51996387)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3S NC_030729.1 (50703280..50718798)

    Chromosome 3S - NC_054376.1Genomic Context describing neighboring genes Neighboring gene LysM, putative peptidoglycan-binding, domain containing 2 S homeolog Neighboring gene tropomodulin 3 S homeolog Neighboring gene mitogen-activated protein kinase 6 S homeolog Neighboring gene uncharacterized LOC121402161

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    acts_upstream_of_or_within transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transcription elongation by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of Cdc73/Paf1 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of Cdc73/Paf1 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    RNA polymerase-associated protein LEO1
    Names
    Leo1, Paf1/RNA polymerase II complex component, homolog

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001091811.2 → NP_001085280.1  RNA polymerase-associated protein LEO1

      See identical proteins and their annotated locations for NP_001085280.1

      Status: PROVISIONAL

      Source sequence(s)
      BC094174
      UniProtKB/Swiss-Prot
      Q52KV5
      UniProtKB/TrEMBL
      A0A974HR72
      Related
      ENSXLAP00005015734.1, ENSXLAT00005016021.1
      Conserved Domains (2) summary
      PHA02664
      Location:63 → 201
      PHA02664; hypothetical protein; Provisional
      pfam04004
      Location:405 → 563
      Leo1; Leo1-like protein

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      51980791..51996387
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q52KV5.1 GenPept UniProtKB/Swiss-Prot:Q52KV5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.