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    vdac1.S voltage-dependent anion channel 1 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 380376, updated on 9-Dec-2024

    Summary

    Official Symbol
    vdac1.S
    Official Full Name
    voltage-dependent anion channel 1 S homeolog
    Primary source
    Xenbase:XB-GENE-955070
    Locus tag
    XELAEV_18019999mg
    See related
    EnsemblRapid:ENSXLAG00005019509 AllianceGenome:Xenbase:XB-GENE-955070
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    vdac1; somi35
    Summary
    Predicted to enable ATP binding activity; porin activity; and voltage-gated monoatomic anion channel activity. Predicted to act upstream of or within apoptotic process and monoatomic anion transmembrane transport. Predicted to be located in membrane raft; mitochondrial outer membrane; and plasma membrane. Predicted to be part of pore complex. Is expressed in mesenchyme; musculoskeletal system; and visual system. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human VDAC1 (voltage dependent anion channel 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See vdac1.S in Genome Data Viewer
    Location:
    chromosome: 3S
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3S NC_054376.1 (13009422..13036753)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3S NC_030729.1 (12788225..12815684)

    Chromosome 3S - NC_054376.1Genomic Context describing neighboring genes Neighboring gene S-phase kinase-associated protein 1 S homeolog Neighboring gene transcription factor 7 S homeolog Neighboring gene chromosome 3 C5orf15 homolog S homeolog Neighboring gene follistatin like 4 S homeolog

    Genomic regions, transcripts, and products

    General gene information

    Clone Names

    • MGC53435

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables porin activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables voltage-gated monoatomic anion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within monoatomic anion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane raft IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of pore complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    voltage-dependent anion channel 1 S homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001087215.1NP_001080684.1  voltage-dependent anion channel 1 S homeolog

      See identical proteins and their annotated locations for NP_001080684.1

      Status: PROVISIONAL

      Source sequence(s)
      BC046577
      UniProtKB/TrEMBL
      A0A974D8J2, Q7ZWZ0
      Related
      ENSXLAP00005057305.1, ENSXLAT00005058652.1
      Conserved Domains (1) summary
      cd07306
      Location:4282
      Porin3_VDAC; Voltage-dependent anion channel of the outer mitochondrial membrane

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      13009422..13036753
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018254085.2XP_018109574.1  voltage-dependent anion channel 1 S homeolog isoform X1

      UniProtKB/TrEMBL
      A0A974D8J2, Q7ZWZ0