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    Lingo2 leucine rich repeat and Ig domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 242384, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lingo2provided by MGI
    Official Full Name
    leucine rich repeat and Ig domain containing 2provided by MGI
    Primary source
    MGI:MGI:2442298
    See related
    Ensembl:ENSMUSG00000045083 AllianceGenome:MGI:2442298
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Lern3; Lrrn6c; B230217C06Rik
    Summary
    Acts upstream of or within positive regulation of synapse assembly. Predicted to be located in glutamatergic synapse and synaptic membrane. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including central nervous system and nose. Orthologous to human LINGO2 (leucine rich repeat and Ig domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cortex adult (RPKM 1.0), CNS E18 (RPKM 0.9) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Lingo2 in Genome Data Viewer
    Location:
    4 A5; 4 17.74 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (35696778..36951929, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (35696778..36951744, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_09942 Neighboring gene predicted gene, 33672 Neighboring gene STARR-seq mESC enhancer starr_09943 Neighboring gene STARR-seq mESC enhancer starr_09944 Neighboring gene high mobility group box 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_09945 Neighboring gene STARR-seq mESC enhancer starr_09946 Neighboring gene STARR-seq mESC enhancer starr_09947 Neighboring gene STARR-seq mESC enhancer starr_09949 Neighboring gene STARR-seq mESC enhancer starr_09950 Neighboring gene predicted gene, 54236 Neighboring gene STARR-seq mESC enhancer starr_09951 Neighboring gene STARR-seq mESC enhancer starr_09952 Neighboring gene STARR-seq mESC enhancer starr_09953 Neighboring gene malate dehydrogenase 2, NAD (mitochondrial) pseudogene Neighboring gene STARR-seq mESC enhancer starr_09954 Neighboring gene STARR-seq mESC enhancer starr_09955 Neighboring gene predicted gene 12370 Neighboring gene STARR-seq mESC enhancer starr_09956 Neighboring gene microRNA 876 Neighboring gene microRNA 873a Neighboring gene microRNA 873b Neighboring gene predicted gene 12371 Neighboring gene predicted gene, 42269

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Roles of lncLingo2 and its derived miR-876-5p in the acquisition of opioid reinforcement. Yang H, et al. Addict Biol, 2024 Feb. PMID 38380802, Free PMC Article
    2. Soluble form of Lingo2, an autism spectrum disorder-associated molecule, functions as an excitatory synapse organizer in neurons. Yoshida F, et al. Transl Psychiatry, 2024 Oct 23. PMID 39443477, Free PMC Article
    3. TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths. Belle NM, et al. Nat Commun, 2019 Sep 27. PMID 31562318, Free PMC Article
    4. Expression of the Lingo/LERN gene family during mouse embryogenesis. Haines BP, et al. Gene Expr Patterns, 2008 Jan. PMID 18297755
    5. Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo. Homma S, et al. Gene Expr Patterns, 2009 Jan. PMID 18848646

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Soluble form of Lingo2, an autism spectrum disorder-associated molecule, functions as an excitatory synapse organizer in neurons.
      Title: Soluble form of Lingo2, an autism spectrum disorder-associated molecule, functions as an excitatory synapse organizer in neurons.
    2. Roles of lncLingo2 and its derived miR-876-5p in the acquisition of opioid reinforcement.
      Title: Roles of lncLingo2 and its derived miR-876-5p in the acquisition of opioid reinforcement.
    3. Data show that trefoil factor 3 (TFF3) - leucine rich repeat receptor and nogo-interacting protein 2 (LINGO2) interactions disrupt EGFR-LINGO2 complexes resulting in enhanced epidermal growth factor receptor (EGFR) signaling.
      Title: TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of synapse assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in synaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2
    Names
    leucine rich repeat neuronal 6C
    leucine-rich repeat neuronal protein 6C

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001165999.1 → NP_001159471.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 precursor

      See identical proteins and their annotated locations for NP_001159471.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. All variants (1-4) encode the same protein.
      Source sequence(s)
      AK139458, AK141568, AL844208, BY651810
      Consensus CDS
      CCDS18040.1
      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Related
      ENSMUSP00000103757.2, ENSMUST00000108122.8
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    2. NM_001166000.1 → NP_001159472.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 precursor

      See identical proteins and their annotated locations for NP_001159472.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All variants (1-4) encode the same protein.
      Source sequence(s)
      AL833783, AL844208, BC090619, BY651810
      Consensus CDS
      CCDS18040.1
      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Related
      ENSMUSP00000095754.3, ENSMUST00000098151.9
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    3. NM_001166001.1 → NP_001159473.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 precursor

      See identical proteins and their annotated locations for NP_001159473.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All variants (1-4) encode the same protein.
      Source sequence(s)
      AL844199, AL844208, BC137866, BY651810
      Consensus CDS
      CCDS18040.1
      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Related
      ENSMUSP00000130423.2, ENSMUST00000164772.8
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    4. NM_175516.4 → NP_780725.2  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 precursor

      See identical proteins and their annotated locations for NP_780725.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All variants (1-4) encode the same protein.
      Source sequence(s)
      AK045639, AL844208, BY651810
      Consensus CDS
      CCDS18040.1
      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Related
      ENSMUSP00000069772.3, ENSMUST00000065173.9
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      35696778..36951929 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164100.1 → XP_036019993.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    2. XM_036164097.1 → XP_036019990.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    3. XM_011250017.4 → XP_011248319.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      See identical proteins and their annotated locations for XP_011248319.1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    4. XM_036164098.1 → XP_036019991.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    5. XM_011250023.4 → XP_011248325.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      See identical proteins and their annotated locations for XP_011248325.1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    6. XM_036164104.1 → XP_036019997.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    7. XM_017320198.2 → XP_017175687.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    8. XM_036164107.1 → XP_036020000.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    9. XM_006537904.5 → XP_006537967.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006537967.1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    10. XM_036164106.1 → XP_036019999.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    11. XM_036164108.1 → XP_036020001.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    12. XM_011250020.4 → XP_011248322.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      See identical proteins and their annotated locations for XP_011248322.1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    13. XM_036164105.1 → XP_036019998.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    14. XM_036164101.1 → XP_036019994.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    15. XM_030253527.2 → XP_030109387.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    16. XM_036164103.1 → XP_036019996.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    17. XM_011250018.4 → XP_011248320.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      See identical proteins and their annotated locations for XP_011248320.1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    18. XM_036164102.1 → XP_036019995.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    19. XM_011250019.4 → XP_011248321.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      See identical proteins and their annotated locations for XP_011248321.1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    20. XM_036164099.1 → XP_036019992.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    21. XM_030253528.2 → XP_030109388.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    22. XM_006537903.4 → XP_006537966.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006537966.1

      UniProtKB/Swiss-Prot
      Q3URE9, Q8BLC0, Q8BZD4
      UniProtKB/TrEMBL
      B2RQD4, B7ZN36
      Conserved Domains (7) summary
      smart00013
      Location:27 → 60
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:355 → 408
      LRRCT; Leucine rich repeat C-terminal domain
      sd00033
      Location:83 → 106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:106 → 165
      LRR_8; Leucine rich repeat
      cd00096
      Location:417 → 421
      Ig; Ig strand A' [structural motif]
      cd21340
      Location:176 → 373
      PPP1R42; protein phosphatase 1 regulatory subunit 42
      cl11960
      Location:411 → 500
      Ig; Immunoglobulin domain

    RNA

    1. XR_004941891.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3URE9.1 GenPept UniProtKB/Swiss-Prot:Q3URE9

    Gene LinkOut

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