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    CG16896 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37977, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG16896provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035073
    Locus tag
    Dmel_CG16896
    See related
    AllianceGenome:FB:FBgn0035073
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG16896
    Summary
    Predicted to enable GTPase activator activity. Predicted to be involved in cilium assembly. Predicted to be active in ciliary basal body. Is expressed in embryonic brain; larval ventral nerve cord; and organism. Orthologous to human TBC1D31 (TBC1 domain family member 31). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG16896 in Genome Data Viewer
    Location:
    60E4-60E4; 2-107 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24871407..24874912, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20758930..20762435, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44829 Neighboring gene Activating transcription factor-2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR43466

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ATF-2 regulates fat metabolism in Drosophila. Okamura T, et al. Mol Biol Cell, 2007 Apr. PMID 17314398, Free PMC Article
    2. Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteins. Gabernet-Castello C, et al. Mol Biol Cell, 2013 May. PMID 23485563, Free PMC Article
    3. Evi5 promotes collective cell migration through its Rab-GAP activity. Laflamme C, et al. J Cell Biol, 2012 Jul 9. PMID 22778279, Free PMC Article
    4. A study of Epstein-Barr virus BRLF1 activity in a Drosophila model system. Adamson A, et al. ScientificWorldJournal, 2012. PMID 22629134, Free PMC Article
    5. Identification of Cellular Genes Involved in Baculovirus GP64 Trafficking to the Plasma Membrane. Hodgson JJ, et al. J Virol, 2022 Jun 22. PMID 35608346, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTPase activator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG16896-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24871407..24874912 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138129.4 → NP_611973.2  uncharacterized protein Dmel_CG16896 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611973.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0Z4
      Related
      FBpp0072328
      Conserved Domains (3) summary
      COG2319
      Location:228 → 467
      WD40; WD40 repeat [General function prediction only]
      cl12013
      Location:766 → 952
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl19107
      Location:817 → 909
      SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T9B7 Q8T9B7
    Q9W0Z4 Q9W0Z4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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