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    CG9676 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32647, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9676provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030773
    Locus tag
    Dmel_CG9676
    See related
    AllianceGenome:FB:FBgn0030773
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9676; SP99
    Summary
    Enables serine hydrolase activity. Predicted to be involved in proteolysis. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9676 in Genome Data Viewer
    Location:
    15A1-15A1; 1-55 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16699152..16700170, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16593185..16594203, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene singles bar Neighboring gene Abnormal X segregation Neighboring gene Septin 4 Neighboring gene uncharacterized protein Neighboring gene spheroide Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The serine protease homolog spheroide is involved in sensing of pathogenic Gram-positive bacteria. Patrnogic J, et al. PLoS One, 2017. PMID 29211760, Free PMC Article
    2. Prevalence of off-target effects in Drosophila RNA interference screens. Ma Y, et al. Nature, 2006 Sep 21. PMID 16964239
    3. Evolution of a cellular immune response in Drosophila: a phenotypic and genomic comparative analysis. Salazar-Jaramillo L, et al. Genome Biol Evol, 2014 Feb. PMID 24443439, Free PMC Article
    4. Use of mutagenesis, genetic mapping and next generation transcriptomics to investigate insecticide resistance mechanisms. Kalajdzic P, et al. PLoS One, 2012. PMID 22768270, Free PMC Article
    5. Development of fly tolerance to consuming a high-protein diet requires physiological, metabolic and transcriptional changes. Yurkevych IS, et al. Biogerontology, 2020 Oct. PMID 32468146

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine hydrolase activity HDA PubMed 
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9676-PA
    NP_728008.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      16699152..16700170 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167535.2 → NP_728008.1  uncharacterized protein Dmel_CG9676 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728008.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXC9
      Related
      FBpp0074138
      Conserved Domains (2) summary
      smart00020
      Location:27 → 245
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:28 → 248
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VXC9 Q9VXC9

    Gene LinkOut

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