Noxred1 NADP+ dependent oxidoreductase domain containing 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Noxred1provided by MGI
Official Full Name: NADP+ dependent oxidoreductase domain containing 1provided by MGI
Primary source: MGI:MGI:1918525
See related: Ensembl:ENSMUSG00000072919 AllianceGenome:MGI:1918525
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 4933437F05Rik
Summary: Predicted to enable pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process. Orthologous to human NOXRED1 (NADP dependent oxidoreductase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in testis adult (RPKM 25.5) and CNS E14 (RPKM 1.2) See more
Orthologs: human all
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Genomic context

Location:: 12 D2; 12 41.42 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (87267897..87285375, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (87221123..87238601, complement)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:236915

NoName (e-PCR)
- UniSTS:492008

AI413782 (e-PCR)
- UniSTS:160238

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables pyrroline-5-carboxylate reductase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in L-proline biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: NADP-dependent oxidoreductase domain-containing protein 1

Names: pyrroline-5-carboxylate reductase-like protein C14orf148 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_027744.1 → NP_082020.1 NADP-dependent oxidoreductase domain-containing protein 1

See identical proteins and their annotated locations for NP_082020.1

Status: PROVISIONAL

Source sequence(s)

BC125331

Consensus CDS

CCDS36502.1

UniProtKB/Swiss-Prot

Q9D3S5

Related

ENSMUSP00000152486.2, ENSMUST00000222480.2

Conserved Domains (1) summary

cl21454
Location:82 → 160

NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins