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    CG32523 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318071, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32523provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052523
    Locus tag
    Dmel_CG32523
    See related
    AllianceGenome:FB:FBgn0052523
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1497; Dmel\CG32523; SP50
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Is expressed in photoreceptor neurons. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32523 in Genome Data Viewer
    Location:
    19F2-19F2; 1-65 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (21217878..21218835)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (21088905..21089862)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene central complex broad Neighboring gene uncharacterized protein Neighboring gene Membrane-bound Notch regulator Neighboring gene transfer RNA:Isoleucine-AAT 2-1 pseudogene Neighboring gene transfer RNA:Arginine-TCG 2-2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster. Rollmann SM, et al. Nat Genet, 2006 Jul. PMID 16783380
    2. Drosophila MSL complex globally acetylates H4K16 on the male X chromosome for dosage compensation. Gelbart ME, et al. Nat Struct Mol Biol, 2009 Aug. PMID 19648925, Free PMC Article
    3. CULD is required for rhodopsin and TRPL channel endocytic trafficking and survival of photoreceptor cells. Xu Y, et al. J Cell Sci, 2016 Jan 15. PMID 26598556, Free PMC Article
    4. The Drosophila Tis11 protein and its effects on mRNA expression in flies. Choi YJ, et al. J Biol Chem, 2014 Dec 19. PMID 25342740, Free PMC Article
    5. Differential gene expression related to Nora virus infection of Drosophila melanogaster. Cordes EJ, et al. Virus Res, 2013 Aug. PMID 23603562, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32523-PA
    NP_728401.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      21217878..21218835
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167738.3 → NP_728401.1  uncharacterized protein Dmel_CG32523 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728401.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQ51
      Related
      FBpp0076886
      Conserved Domains (2) summary
      smart00020
      Location:36 → 256
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:37 → 219
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQ51 Q8IQ51

    Gene LinkOut

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