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    CG13930 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38210, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13930provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035256
    Locus tag
    Dmel_CG13930
    See related
    AllianceGenome:FB:FBgn0035256
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13930
    Summary
    Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in cilium movement. Predicted to be part of axonemal dynein complex. Is expressed in chordotonal neurons. Orthologous to human DNAI4 (dynein axonemal intermediate chain 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13930 in Genome Data Viewer
    Location:
    62A10-62A10; 3-0.5 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1670407..1672727, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1670407..1672727, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene snoRNA:Orphan C/D box 15 Neighboring gene Ribosomal protein L23A Neighboring gene U snoRNA host gene 7 Neighboring gene RabX5 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A molecular genetic analysis of the interaction between the cytoplasmic dynein intermediate chain and the glued (dynactin) complex. Boylan K, et al. Mol Biol Cell, 2000 Nov. PMID 11071907, Free PMC Article
    2. Diverse Roles of Axonemal Dyneins in Drosophila Auditory Neuron Function and Mechanical Amplification in Hearing. Karak S, et al. Sci Rep, 2015 Nov 26. PMID 26608786, Free PMC Article
    3. Forkhead transcription factor Fd3F cooperates with Rfx to regulate a gene expression program for mechanosensory cilia specialization. Newton FG, et al. Dev Cell, 2012 Jun 12. PMID 22698283, Free PMC Article
    4. Dyneins across eukaryotes: a comparative genomic analysis. Wickstead B, et al. Traffic, 2007 Dec. PMID 17897317, Free PMC Article
    5. Chromatin immunoprecipitation reveals a novel role for the Drosophila SoxNeuro transcription factor in axonal patterning. Girard F, et al. Dev Biol, 2006 Nov 15. PMID 16979619

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables dynein heavy chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dynein light chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cilium movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cilium movement ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of axonemal dynein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of axonemal dynein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13930-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1670407..1672727 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139388.2 → NP_647645.1  uncharacterized protein Dmel_CG13930 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647645.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D6W4W3, Q9W0A6
      Related
      FBpp0072685
      Conserved Domains (3) summary
      COG2319
      Location:279 → 648
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:524 → 560
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:518 → 593
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W0A6 Q9W0A6

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