U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    TwdlV TweedleV [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40537, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    TwdlVprovided by FlyBase
    Official Full Name
    TweedleVprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037227
    Locus tag
    Dmel_CG14640
    See related
    AllianceGenome:FB:FBgn0037227
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14640; Dmel\CG14640
    Summary
    Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be located in extracellular matrix. Predicted to be active in chitin-based extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See TwdlV in Genome Data Viewer
    Location:
    82A1-82A1; 3-47.1 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4254708..4255833)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (80430..81555)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene TweedleG Neighboring gene uncharacterized protein Neighboring gene Odorant receptor 82a Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. MOD(MDG4)-64.2 protein, isoform of MOD(MDG4) loci, directly interacts with the Tweedle protein family of Drosophila melanogaster. Golovnin AK, et al. Dokl Biochem Biophys, 2013 Sep. PMID 24150578
    2. tBRD-1 and tBRD-2 regulate expression of genes necessary for spermatid differentiation. Theofel I, et al. Biol Open, 2017 Apr 15. PMID 28235844, Free PMC Article
    3. Transcriptome analysis of Drosophila suzukii reveals molecular mechanisms conferring pyrethroid and spinosad resistance. Tabuloc CA, et al. Sci Rep, 2024 Aug 27. PMID 39191909, Free PMC Article
    4. tBRD-1 selectively controls gene activity in the Drosophila testis and interacts with two new members of the bromodomain and extra-terminal (BET) family. Theofel I, et al. PLoS One, 2014. PMID 25251222, Free PMC Article
    5. High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae. Wang M, et al. Dev Cell, 2022 May 23. PMID 35512700

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based cuticle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables structural constituent of chitin-based larval cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chitin-based cuticle development ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in chitin-based extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    TweedleV
    Names
    CG14640-PA
    TwdlV-PA
    tweedle
    tweedle V

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      4254708..4255833
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141189.2 → NP_649446.1  TweedleV [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649446.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMZ8
      Related
      FBpp0078615
      Conserved Domains (1) summary
      smart00690
      Location:78 → 173
      DM5; Domain of unknown function, currently peculiar to Drosophila
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMZ8 Q9VMZ8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools