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    Vha36-1 Vacuolar H[+] ATPase 36kD subunit 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44702, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vha36-1provided by FlyBase
    Official Full Name
    Vacuolar H[+] ATPase 36kD subunit 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0022097
    Locus tag
    Dmel_CG8186
    See related
    AllianceGenome:FB:FBgn0022097
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0153538.20; anon-WO0153538.21; anon-WO0153538.28; anon-WO02059370.27; ATP6V1D; CG8186; Dmel\CG8186; l(2)k07207; vha36; Vha36; vha36-1; VhaD
    Summary
    Predicted to contribute to proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Part of plasma membrane proton-transporting V-type ATPase complex. Is expressed in several structures, including Malpighian tubule; adult head; adult heart; embryonic/larval midgut primordium; and gut section. Orthologous to human ATP6V1D (ATPase H+ transporting V1 subunit D). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Vha36-1 in Genome Data Viewer
    Location:
    52A10-52A10; 2-74 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (15541435..15542498)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11428940..11430003)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45927 Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation initiation factor 2B subunit gamma Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Vacuole dynamics in the salivary glands of Drosophila melanogaster during prepupal development. Farkaš R, et al. Dev Growth Differ, 2015 Jan. PMID 25611296
    2. Recent origins of sperm genes in Drosophila. Dorus S, et al. Mol Biol Evol, 2008 Oct. PMID 18653731, Free PMC Article
    3. The RagA GTPase protects young egg chambers in Drosophila. Zhou Y, et al. Cell Rep, 2023 Jun 27. PMID 37302067
    4. Quality of regulatory elements in Drosophila retrogenes. Bai Y, et al. Genomics, 2009 Jan. PMID 18848618, Free PMC Article
    5. Lysosomal Degradation Is Required for Sustained Phagocytosis of Bacteria by Macrophages. Wong CO, et al. Cell Host Microbe, 2017 Jun 14. PMID 28579255, Free PMC Article

    See all (59) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    contributes_to proton-transporting ATPase activity, rotational mechanism IC
    Inferred by Curator
    more info
    		 PubMed 
    enables proton-transporting ATPase activity, rotational mechanism IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proton transmembrane transport IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of plasma membrane proton-transporting V-type ATPase complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    part_of proton-transporting V-type ATPase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of vacuolar proton-transporting V-type ATPase, V1 domain ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vacuolar H[+] ATPase 36kD subunit 1
    Names
    CG8186-PA
    Vha36
    Vha36-1-PA
    vacuolar H-ATPase subunit D
    vacuolar H[+] ATPase subunit 36-1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      15541435..15542498
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143730.3 → NP_651987.1  vacuolar H[+] ATPase 36kD subunit 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651987.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V7D2
      Related
      FBpp0086468
      Conserved Domains (1) summary
      pfam01813
      Location:17 → 207
      ATP-synt_D; ATP synthase subunit D
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V7D2.1 Q9V7D2

    Gene LinkOut

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