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    dmt dalmatian [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41180, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dmtprovided by FlyBase
    Official Full Name
    dalmatianprovided by FlyBase
    Primary source
    FLYBASE:FBgn0278604
    Locus tag
    Dmel_CG8374
    See related
    AllianceGenome:FB:FBgn0278604
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    0481/03; anon-WO0118547.317; aul; CG8374; Dmel\CG8374; Dmt; s048103
    Summary
    Involved in several processes, including mitotic sister chromatid cohesion; respiratory system development; and salivary gland development. Located in heterochromatin. Is expressed in several structures, including embryonic/larval gut; embryonic/larval posterior spiracle; presumptive embryonic/larval system; and primordial germ cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See dmt in Genome Data Viewer
    Location:
    85E5-85E5; 3-49 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9711142..9714675)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5536864..5540397)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Uncoordinated 115a Neighboring gene trabid Neighboring gene small Cajal body-specific RNA : PsiU1-6 Neighboring gene hyperplastic discs Neighboring gene Forkhead box P Neighboring gene alpha-Tubulin at 85E

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Staying alive: dalmation mediated blocking of apoptosis is essential for tissue maintenance. Kerman BE, et al. Dev Dyn, 2010 Jun. PMID 20503358, Free PMC Article
    2. Brca2, Pds5 and Wapl differentially control cohesin chromosome association and function. Misulovin Z, et al. PLoS Genet, 2018 Feb. PMID 29447171, Free PMC Article
    3. Full circle: a brief history of cohesin and the regulation of gene expression. Horsfield JA. FEBS J, 2023 Apr. PMID 35048511
    4. Drosophila Dalmatian combines sororin and shugoshin roles in establishment and protection of cohesion. Yamada T, et al. EMBO J, 2017 Jun 1. PMID 28483815, Free PMC Article
    5. Naa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion. Ribeiro AL, et al. Sci Rep, 2016 Dec 20. PMID 27996020, Free PMC Article

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in cellular response to radiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    NOT involved_in mitotic spindle assembly checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in peripheral nervous system development TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in primary branching, open tracheal system IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in salivary gland development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in trachea development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dalmatian
    Names
    CG8374-PA
    anduril
    dalmation
    dmt-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9711142..9714675
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079571.2 → NP_524295.1  dalmatian [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524295.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9U449, Q9VH89
      Related
      FBpp0081564
      Conserved Domains (1) summary
      pfam09666
      Location:490 → 635
      Sororin; Sororin protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VH89.1 Q9VH89

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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