Trim9 tripartite motif-containing 9 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Trim9provided by MGI
Official Full Name: tripartite motif-containing 9provided by MGI
Primary source: MGI:MGI:2137354
See related: Ensembl:ENSMUSG00000021071 AllianceGenome:MGI:2137354
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable several functions, including SNARE binding activity; protein homodimerization activity; and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of SNARE complex assembly; negative regulation of calcium ion-dependent exocytosis; and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within synaptic vesicle exocytosis. Located in cytoplasm and dendrite. Is expressed in several structures, including alimentary system; limb; nervous system; sensory organ; and urinary system. Orthologous to human TRIM9 (tripartite motif containing 9). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in frontal lobe adult (RPKM 15.7), cortex adult (RPKM 12.9) and 5 other tissues See more
Orthologs: human all
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Genomic context

Location:: 12 C2; 12 29.07 cM

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (70291307..70394404, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (70244533..70347869, complement)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1.
Title: The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1.
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.
Title: The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.
MicroRNA-653 Inhibits Thymocyte Proliferation and Induces Thymocyte Apoptosis in Mice with Autoimmune Myasthenia Gravis by Downregulating TRIM9.
Title: MicroRNA-653 Inhibits Thymocyte Proliferation and Induces Thymocyte Apoptosis in Mice with Autoimmune Myasthenia Gravis by Downregulating TRIM9.
Findings reveal that TRIM9 is essential for resolving NF-kappaB-dependent neuroinflammation to promote recovery and repair after brain injury.
Title: TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice.
Authors demonstrate that tripartite motif protein 9 (TRIM9)-dependent ubiquitination of DCC blocks the interaction with and phosphorylation of FAK.
Title: TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching.
Adult-born dentate granule cells lacking Trim9 exhibited excessive dendritic arborization and mislocalization of cell bodies in vivo
Title: Trim9 Deletion Alters the Morphogenesis of Developing and Adult-Born Hippocampal Neurons and Impairs Spatial Learning and Memory.
a gradient of TRIM9-mediated ubiquitination of VASP creates a filopodial stability gradient during axon turning
Title: The E3 Ubiquitin Ligase TRIM9 Is a Filopodia Off Switch Required for Netrin-Dependent Axon Guidance.
TRIM9 is expressed in the mouse embryonic and adult nervous system
Title: TRIM9 is specifically expressed in the embryonic and adult nervous system.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)
Targeted (3) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AU048745 (e-PCR)
- UniSTS:145195

AI835002 (e-PCR)
- UniSTS:164503

17.MMHAP9FRF8.seq (e-PCR)
- UniSTS:123362

Trim9 (e-PCR), detects polymorphism
- UniSTS:507889

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables SNARE binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein domain specific binding	ISO Inferred from Sequence Orthology more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info
enables ubiquitin protein ligase activity	ISO Inferred from Sequence Orthology more info
enables ubiquitin protein ligase activity	ISS Inferred from Sequence or Structural Similarity more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in negative regulation of SNARE complex assembly	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of calcium ion-dependent exocytosis	ISO Inferred from Sequence Orthology more info
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	ISO Inferred from Sequence Orthology more info
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within synaptic vesicle exocytosis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in dendrite	ISO Inferred from Sequence Orthology more info
is_active_in presynaptic cytosol	ISO Inferred from Sequence Orthology more info
located_in synaptic vesicle	IEA Inferred from Electronic Annotation more info
is_active_in synaptic vesicle	ISO Inferred from Sequence Orthology more info
located_in synaptic vesicle	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: E3 ubiquitin-protein ligase TRIM9

Names: RING-type E3 ubiquitin transferase TRIM9; tripartite motif-containing protein 9

NP_001103672.1

EC 2.3.2.27

NP_001103673.1

EC 2.3.2.27

NP_001273315.1

EC 2.3.2.27

NP_001273316.1

EC 2.3.2.27

NP_001273317.1

EC 2.3.2.27

NP_001392290.1

EC 2.3.2.27

NP_001392291.1

EC 2.3.2.27

NP_001392292.1

EC 2.3.2.27

NP_001392293.1

EC 2.3.2.27

NP_001392294.1

EC 2.3.2.27

NP_001392295.1

EC 2.3.2.27

NP_001392296.1

EC 2.3.2.27

NP_001392297.1

EC 2.3.2.27

NP_001392298.1

EC 2.3.2.27

NP_001392299.1

EC 2.3.2.27

NP_001392300.1

EC 2.3.2.27

NP_001392301.1

EC 2.3.2.27

NP_001392302.1

EC 2.3.2.27

NP_001392303.1

EC 2.3.2.27

NP_001392304.1

EC 2.3.2.27

NP_001392305.1

EC 2.3.2.27

NP_001392306.1

EC 2.3.2.27

NP_001392307.1

EC 2.3.2.27

NP_001392308.1

EC 2.3.2.27

NP_001392309.1

EC 2.3.2.27

NP_001392310.1

EC 2.3.2.27

NP_001392311.1

EC 2.3.2.27

NP_001392312.1

EC 2.3.2.27

NP_001392313.1

EC 2.3.2.27

NP_001392314.1

EC 2.3.2.27

NP_001392315.1

EC 2.3.2.27

NP_001392316.1

EC 2.3.2.27

NP_444397.2

EC 2.3.2.27

XP_006516465.1

EC 2.3.2.27

XP_017170752.1

EC 2.3.2.27

XP_017170754.1

EC 2.3.2.27

XP_030102867.1

EC 2.3.2.27

XP_036013585.1

EC 2.3.2.27

XP_036013586.1

EC 2.3.2.27

XP_036013588.1

EC 2.3.2.27

XP_036013589.1

EC 2.3.2.27

XP_036013591.1

EC 2.3.2.27

XP_036013592.1

EC 2.3.2.27

XP_036013596.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001110202.2 → NP_001103672.1 E3 ubiquitin-protein ligase TRIM9 isoform 2

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

Consensus CDS

CCDS49077.1

UniProtKB/TrEMBL

A0A1Y7VJX8

Related

ENSMUSP00000106149.3, ENSMUST00000110520.10

Conserved Domains (6) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:557 → 704

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

cd16755
Location:5 → 52

RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19826
Location:223 → 271

Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19843
Location:166 → 212

Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
NM_001110203.2 → NP_001103673.1 E3 ubiquitin-protein ligase TRIM9 isoform 3

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

Consensus CDS

CCDS49079.1

UniProtKB/TrEMBL

E9Q524

Related

ENSMUSP00000127081.2, ENSMUST00000167755.3

Conserved Domains (4) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cl00034
Location:223 → 271

Bbox_SF; B-box-type zinc finger superfamily

cl17238
Location:5 → 52

RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
NM_001286386.2 → NP_001273315.1 E3 ubiquitin-protein ligase TRIM9 isoform 4

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

Consensus CDS

CCDS88348.1

UniProtKB/Swiss-Prot

Q8C7M3

Related

ENSMUSP00000152692.2, ENSMUST00000221370.2

Conserved Domains (4) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cl00034
Location:223 → 271

Bbox_SF; B-box-type zinc finger superfamily

cl17238
Location:5 → 52

RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
NM_001286387.2 → NP_001273316.1 E3 ubiquitin-protein ligase TRIM9 isoform 5

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8, Q3TR28

Conserved Domains (6) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:630 → 777

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

cd16755
Location:5 → 52

RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19826
Location:223 → 271

Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19843
Location:166 → 212

Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
NM_001286388.2 → NP_001273317.1 E3 ubiquitin-protein ligase TRIM9 isoform 6

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8

Conserved Domains (6) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:631 → 796

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

cd16755
Location:5 → 52

RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19826
Location:223 → 271

Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19843
Location:166 → 212

Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
NM_001405361.1 → NP_001392290.1 E3 ubiquitin-protein ligase TRIM9 isoform 7

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/Swiss-Prot

Q6ZQE5, Q80WT6, Q8C7M3, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3

UniProtKB/TrEMBL

A0A1Y7VJX8

Related

ENSMUSP00000152147.2, ENSMUST00000222316.2
NM_001405362.1 → NP_001392291.1 E3 ubiquitin-protein ligase TRIM9 isoform 8

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405363.1 → NP_001392292.1 E3 ubiquitin-protein ligase TRIM9 isoform 9

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405364.1 → NP_001392293.1 E3 ubiquitin-protein ligase TRIM9 isoform 10

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405365.1 → NP_001392294.1 E3 ubiquitin-protein ligase TRIM9 isoform 11

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405366.1 → NP_001392295.1 E3 ubiquitin-protein ligase TRIM9 isoform 12

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405367.1 → NP_001392296.1 E3 ubiquitin-protein ligase TRIM9 isoform 13

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405368.1 → NP_001392297.1 E3 ubiquitin-protein ligase TRIM9 isoform 14

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405369.1 → NP_001392298.1 E3 ubiquitin-protein ligase TRIM9 isoform 15

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405370.1 → NP_001392299.1 E3 ubiquitin-protein ligase TRIM9 isoform 16

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405371.1 → NP_001392300.1 E3 ubiquitin-protein ligase TRIM9 isoform 17

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8, A0A1Y7VP88

Related

ENSMUSP00000152887.2, ENSMUST00000223160.2
NM_001405372.1 → NP_001392301.1 E3 ubiquitin-protein ligase TRIM9 isoform 18

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405373.1 → NP_001392302.1 E3 ubiquitin-protein ligase TRIM9 isoform 19

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405374.1 → NP_001392303.1 E3 ubiquitin-protein ligase TRIM9 isoform 20

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A1Y7VJX8
NM_001405375.1 → NP_001392304.1 E3 ubiquitin-protein ligase TRIM9 isoform 21

Status: VALIDATED

Source sequence(s)

AC124733, AC147241
NM_001405376.1 → NP_001392305.1 E3 ubiquitin-protein ligase TRIM9 isoform 22

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

Related

ENSMUSP00000152496.2, ENSMUST00000221041.2
NM_001405377.1 → NP_001392306.1 E3 ubiquitin-protein ligase TRIM9 isoform 23

Status: VALIDATED

Source sequence(s)

AC124733, AC147241
NM_001405378.1 → NP_001392307.1 E3 ubiquitin-protein ligase TRIM9 isoform 24

Status: VALIDATED

Source sequence(s)

AC124733, AC147241
NM_001405379.1 → NP_001392308.1 E3 ubiquitin-protein ligase TRIM9 isoform 25

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A6I8MWZ7
NM_001405380.1 → NP_001392309.1 E3 ubiquitin-protein ligase TRIM9 isoform 25

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

UniProtKB/TrEMBL

A0A6I8MWZ7

Related

ENSMUSP00000159335.2, ENSMUST00000222603.3
NM_001405381.1 → NP_001392310.1 E3 ubiquitin-protein ligase TRIM9 isoform 27

Status: VALIDATED

Source sequence(s)

AC124733, AC147241
NM_001405382.1 → NP_001392311.1 E3 ubiquitin-protein ligase TRIM9 isoform 28

Status: VALIDATED

Source sequence(s)

AC124733, AC147241
NM_001405383.1 → NP_001392312.1 E3 ubiquitin-protein ligase TRIM9 isoform 29

Status: VALIDATED

Source sequence(s)

AC147241
NM_001405384.1 → NP_001392313.1 E3 ubiquitin-protein ligase TRIM9 isoform 30

Status: VALIDATED

Source sequence(s)

AC124733, AC147241
NM_001405385.1 → NP_001392314.1 E3 ubiquitin-protein ligase TRIM9 isoform 31

Status: VALIDATED

Source sequence(s)

AC147241
NM_001405386.1 → NP_001392315.1 E3 ubiquitin-protein ligase TRIM9 isoform 32

Status: VALIDATED

Source sequence(s)

AC147241
NM_001405387.1 → NP_001392316.1 E3 ubiquitin-protein ligase TRIM9 isoform 33

Status: VALIDATED

Source sequence(s)

AC147241
NM_053167.4 → NP_444397.2 E3 ubiquitin-protein ligase TRIM9 isoform 1

Status: VALIDATED

Source sequence(s)

AC124733, AC147241

Consensus CDS

CCDS49078.1

UniProtKB/TrEMBL

A0A1Y7VJX8, E9QLH4

Related

ENSMUSP00000106151.3, ENSMUST00000110522.10

Conserved Domains (6) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:631 → 778

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

cd16755
Location:5 → 52

RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19826
Location:223 → 271

Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19843
Location:166 → 212

Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000078.7 Reference GRCm39 C57BL/6J

Range

70291307..70394404 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036157695.1 → XP_036013588.1 E3 ubiquitin-protein ligase TRIM9 isoform X14

UniProtKB/TrEMBL

A0A1Y7VJX8

Conserved Domains (6) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:529 → 690

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

cd16755
Location:5 → 52

RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19826
Location:223 → 271

Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19843
Location:166 → 212

Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
XM_030247007.2 → XP_030102867.1 E3 ubiquitin-protein ligase TRIM9 isoform X6

UniProtKB/TrEMBL

A0A1Y7VJX8

Conserved Domains (6) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:620 → 767

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

cd16755
Location:5 → 52

RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19826
Location:223 → 271

Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19843
Location:166 → 212

Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
XM_006516402.5 → XP_006516465.1 E3 ubiquitin-protein ligase TRIM9 isoform X8

UniProtKB/TrEMBL

A0A1Y7VJX8

Conserved Domains (6) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:567 → 732

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

cd16755
Location:5 → 52

RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19826
Location:223 → 271

Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19843
Location:166 → 212

Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
XM_036157693.1 → XP_036013586.1 E3 ubiquitin-protein ligase TRIM9 isoform X9

UniProtKB/TrEMBL

A0A1Y7VJX8

Conserved Domains (6) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:560 → 725

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

cd16755
Location:5 → 52

RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19826
Location:223 → 271

Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19843
Location:166 → 212

Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
XM_017315265.3 → XP_017170754.1 E3 ubiquitin-protein ligase TRIM9 isoform X7

UniProtKB/TrEMBL

A0A1Y7VJX8

Conserved Domains (6) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:568 → 733

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

cd16755
Location:5 → 52

RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19826
Location:223 → 271

Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19843
Location:166 → 212

Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
XM_017315263.3 → XP_017170752.1 E3 ubiquitin-protein ligase TRIM9 isoform X3

UniProtKB/TrEMBL

A0A1Y7VJX8

Conserved Domains (6) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:623 → 788

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

cd16755
Location:5 → 52

RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19826
Location:223 → 271

Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19843
Location:166 → 212

Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
XM_036157692.1 → XP_036013585.1 E3 ubiquitin-protein ligase TRIM9 isoform X2

UniProtKB/TrEMBL

A0A1Y7VJX8

Conserved Domains (6) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:631 → 786

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

cd16755
Location:5 → 52

RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19826
Location:223 → 271

Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

cd19843
Location:166 → 212

Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
XM_036157696.1 → XP_036013589.1 E3 ubiquitin-protein ligase TRIM9 isoform X17

Conserved Domains (3) summary

smart00502
Location:27 → 150

BBC; B-Box C-terminal domain

cd00063
Location:204 → 283

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:382 → 547

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
XM_036157699.1 → XP_036013592.1 E3 ubiquitin-protein ligase TRIM9 isoform X20

Conserved Domains (3) summary

smart00502
Location:1 → 99

BBC; B-Box C-terminal domain

cd00063
Location:153 → 232

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:331 → 496

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
XM_036157703.1 → XP_036013596.1 E3 ubiquitin-protein ligase TRIM9 isoform X23

Conserved Domains (3) summary

smart00502
Location:1 → 99

BBC; B-Box C-terminal domain

cd00063
Location:153 → 232

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12889
Location:229 → 396

SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
XM_036157698.1 → XP_036013591.1 E3 ubiquitin-protein ligase TRIM9 isoform X18

UniProtKB/TrEMBL

A0A6I8MWZ7

Conserved Domains (5) summary

smart00502
Location:273 → 399

BBC; B-Box C-terminal domain

cd00063
Location:453 → 532

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00162
Location:10 → 49

RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]

cl00034
Location:223 → 271

Bbox_SF; B-box-type zinc finger superfamily

cl17238
Location:5 → 52

RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain