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    COX9 cytochrome c oxidase subunit VIIa [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851492, updated on 9-Dec-2024

    Summary

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    Official Symbol
    COX9
    Official Full Name
    cytochrome c oxidase subunit VIIa
    Primary source
    SGD:S000002225
    Locus tag
    YDL067C
    See related
    AllianceGenome:SGD:S000002225; FungiDB:YDL067C; VEuPathDB:YDL067C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Contributes to cytochrome-c oxidase activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Part of respiratory chain complex IV. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See COX9 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (334217..334396, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Bdf2p Neighboring gene Cbs1p Neighboring gene isocitrate dehydrogenase (NADP(+)) IDP1 Neighboring gene Pex19p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial import of cytochrome c oxidase subunit VIIa in Saccharomyces cerevisiae. Identification of sequences required for mitochondrial localization in vivo. Duhl DM, et al. J Biol Chem, 1990 May 5. PMID 2158998
    2. Characterization of Paracoccidioides brasiliensis COX9, COX12, and COX16 respiratory genes. Bandeira SC, et al. Mycol Res, 2008 Dec. PMID 18672058
    3. Characterization of COX9, the nuclear gene encoding the yeast mitochondrial protein cytochrome c oxidase subunit VIIa. Subunit VIIa lacks a leader peptide and is an essential component of the holoenzyme. Wright RM, et al. J Biol Chem, 1986 Dec 25. PMID 3023385
    4. Subunits Rip1p and Cox9p of the respiratory chain contribute to diclofenac-induced mitochondrial dysfunction. van Leeuwen JS, et al. Microbiology (Reading), 2011 Mar. PMID 21148204
    5. Nuclear functions required for cytochrome c oxidase biogenesis in Saccharomyces cerevisiae. Characterization of mutants in 34 complementation groups. McEwen JE, et al. J Biol Chem, 1986 Sep 5. PMID 3017950

    See all (65) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    contributes_to cytochrome-c oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to cytochrome-c oxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, cytochrome c to oxygen IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial electron transport, cytochrome c to oxygen IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitochondrial electron transport, cytochrome c to oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in oxidative phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex IV IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome c oxidase subunit VIIa
    NP_010216.1
    • Subunit VIIa of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      334217..334396 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180126.1 → NP_010216.1  TPA: cytochrome c oxidase subunit VIIa [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010216.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRT0, P07255
      UniProtKB/TrEMBL
      N1P613
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P07255.2

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