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    TIR3 Tir3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854804, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TIR3
    Official Full Name
    Tir3p
    Primary source
    SGD:S000001273
    Locus tag
    YIL011W
    See related
    AllianceGenome:SGD:S000001273; FungiDB:YIL011W; VEuPathDB:YIL011W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YIB1
    Summary
    Predicted to be a structural constituent of cell wall. Predicted to be involved in fungal-type cell wall organization. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See TIR3 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (333727..334536)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette multidrug transporter PDR11 Neighboring gene uncharacterized protein Neighboring gene thioredoxin peroxidase DOT5 Neighboring gene telomerase subunit EST3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Induction of DAN/TIR yeast cell wall mannoprotein genes in response to high hydrostatic pressure and low temperature. Abe F. FEBS Lett, 2007 Oct 16. PMID 17910955
    2. Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene expression in Saccharomyces cerevisiae. Abramova N, et al. J Bacteriol, 2001 May. PMID 11292809, Free PMC Article
    3. Impact of Fungal MAPK Pathway Targets on the Cell Wall. Chow J, et al. J Fungi (Basel), 2018 Aug 9. PMID 30096860, Free PMC Article
    4. Identification by comparative transcriptomics of core regulatory genes for higher alcohol production in a top-fermenting yeast at different temperatures in beer fermentation. Sun ZG, et al. Appl Microbiol Biotechnol, 2019 Jun. PMID 31073877
    5. Defining Functions of Mannoproteins in Saccharomyces cerevisiae by High-Dimensional Morphological Phenotyping. Ghanegolmohammadi F, et al. J Fungi (Basel), 2021 Sep 17. PMID 34575807, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables structural constituent of cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in fungal-type cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tir3p
    NP_012254.1
    • Cell wall mannoprotein; member of Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; TIR3 has a paralog, TIR2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      333727..334536
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179361.1 → NP_012254.1  TPA: Tir3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012254.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVR8, P40552
      UniProtKB/TrEMBL
      N1P0P0
      Conserved Domains (1) summary
      pfam00660
      Location:20 → 116
      SRP1_TIP1; Seripauperin and TIP1 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40552.1

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