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    BAP3 amino acid transporter BAP3 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851616, updated on 9-Dec-2024

    Summary

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    Official Symbol
    BAP3
    Official Full Name
    amino acid transporter BAP3
    Primary source
    SGD:S000002453
    Locus tag
    YDR046C
    See related
    AllianceGenome:SGD:S000002453; FungiDB:YDR046C; VEuPathDB:YDR046C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    PAP1
    Summary
    Enables amino acid transmembrane transporter activity. Involved in amino acid transport and transmembrane transport. Located in endoplasmic reticulum and mitochondrion. Human ortholog(s) of this gene implicated in retinitis pigmentosa 68. Orthologous to several human genes including SLC7A1 (solute carrier family 7 member 1); SLC7A14 (solute carrier family 7 member 14); and SLC7A2 (solute carrier family 7 member 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See BAP3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (548762..550576, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene coproporphyrinogen oxidase Neighboring gene DNA-directed RNA polymerase III core subunit RPC11 Neighboring gene uroporphyrinogen decarboxylase HEM12 Neighboring gene Vms1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning and chromosomal organization of a gene encoding a putative amino-acid permease from Saccharomyces cerevisiae. Mai B, et al. Gene, 1994 May 27. PMID 8200527
    2. The permease homologue Ssy1p controls the expression of amino acid and peptide transporter genes in Saccharomyces cerevisiae. Didion T, et al. Mol Microbiol, 1998 Feb. PMID 9489675
    3. Stp1p, Stp2p and Abf1p are involved in regulation of expression of the amino acid transporter gene BAP3 of Saccharomyces cerevisiae. de Boer M, et al. Nucleic Acids Res, 2000 Feb 15. PMID 10648791, Free PMC Article
    4. Regulation of expression of the amino acid transporter gene BAP3 in Saccharomyces cerevisiae. De Boer M, et al. Mol Microbiol, 1998 Nov. PMID 9822825
    5. Cysteine uptake by Saccharomyces cerevisiae is accomplished by multiple permeases. Düring-Olsen L, et al. Curr Genet, 1999 Jul. PMID 10467005

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables amino acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    amino acid transporter BAP3
    NP_010331.3
    • Amino acid permease; involved in uptake of cysteine, leucine, isoleucine and valine; BAP3 has a paralog, BAP2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      548762..550576 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180354.3 → NP_010331.3  TPA: amino acid transporter BAP3 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010331.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VS34, P41815
      UniProtKB/TrEMBL
      A6ZY13, B3LGM1, C7GTA3
      Conserved Domains (1) summary
      COG0833
      Location:40 → 603
      LysP; Amino acid permease [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P41815.2

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