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    Idi1 isopentenyl-diphosphate delta isomerase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 89784, updated on 27-Nov-2024

    Summary

    Official Symbol
    Idi1provided by RGD
    Official Full Name
    isopentenyl-diphosphate delta isomerase 1provided by RGD
    Primary source
    RGD:621835
    See related
    EnsemblRapid:ENSRNOG00000016690 AllianceGenome:RGD:621835
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable isopentenyl-diphosphate delta-isomerase activity; magnesium ion binding activity; and manganese ion binding activity. Predicted to be involved in isopentenyl diphosphate biosynthetic process and response to stilbenoid. Located in peroxisome. Orthologous to human IDI1 (isopentenyl-diphosphate delta isomerase 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Liver (RPKM 279.1), Brain (RPKM 179.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Idi1 in Genome Data Viewer
    Location:
    17q12.1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (66539761..66547524, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (61629592..61637357, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (57976266..57984036, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100911936 Neighboring gene uncharacterized LOC134482733 Neighboring gene uncharacterized LOC134482867 Neighboring gene WD repeat domain 37 Neighboring gene adenosine deaminase RNA specific B2 Neighboring gene uncharacterized LOC134482734

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC108635

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables isopentenyl-diphosphate delta-isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables isopentenyl-diphosphate delta-isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables isopentenyl-diphosphate delta-isomerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables isopentenyl-diphosphate delta-isomerase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables magnesium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables manganese ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cholesterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cholesterol biosynthetic process TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in dimethylallyl diphosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in isopentenyl diphosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in isoprenoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in isoprenoid biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to stilbenoid ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    isopentenyl-diphosphate Delta-isomerase 1
    Names
    IPP isomerase 1
    IPPI1
    isopentenyl pyrophosphate isomerase 1
    NP_445991.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053539.2NP_445991.2  isopentenyl-diphosphate Delta-isomerase 1

      See identical proteins and their annotated locations for NP_445991.2

      Status: VALIDATED

      Source sequence(s)
      BC089786, BF389837, BP491941, BP500454, FM059509
      UniProtKB/TrEMBL
      A0A0H2UHN2, A0A8I5ZLV9, A6KRN6
      Related
      ENSRNOP00000022389.5, ENSRNOT00000022389.8
      Conserved Domains (2) summary
      COG1443
      Location:75278
      Idi; Isopentenyldiphosphate isomerase [Lipid transport and metabolism]
      cl00447
      Location:56283
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      66539761..66547524 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)