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    Uqcc2 ubiquinol-cytochrome c reductase complex assembly factor 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361805, updated on 27-Nov-2024

    Summary

    Official Symbol
    Uqcc2provided by RGD
    Official Full Name
    ubiquinol-cytochrome c reductase complex assembly factor 2provided by RGD
    Primary source
    RGD:1306917
    See related
    EnsemblRapid:ENSRNOG00000025909 AllianceGenome:RGD:1306917
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    M19; Mnf1; RGD1306917
    Summary
    Predicted to be involved in several processes, including mitochondrial respiratory chain complex III assembly; positive regulation of mitochondrial translation; and regulation of insulin secretion. Predicted to be located in mitochondrion and nuclear body. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 7. Orthologous to human UQCC2 (ubiquinol-cytochrome c reductase complex assembly factor 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 325.3), Heart (RPKM 258.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Uqcc2 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (5204682..5217080, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (5202837..5214541, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (5712200..5723902, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene inositol 1,4,5-trisphosphate receptor, type 3 Neighboring gene uncharacterized LOC134483859 Neighboring gene uncharacterized LOC120098963 Neighboring gene inositol hexakisphosphate kinase 3 Neighboring gene uncharacterized LOC108353257

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrial intermembrane space ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial intermembrane space ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrial nucleoid IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial nucleoid ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial nucleoid ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ubiquinol-cytochrome-c reductase complex assembly factor 2
    Names
    mitochondrial nucleoid factor 1
    mitochondrial protein M19
    NP_001101998.1
    XP_038954739.1
    XP_038954740.1
    XP_038954741.1
    XP_063135283.1
    XP_063135284.1
    XP_063135285.1
    XP_063135286.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108528.1NP_001101998.1  ubiquinol-cytochrome-c reductase complex assembly factor 2

      See identical proteins and their annotated locations for NP_001101998.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473988
      UniProtKB/Swiss-Prot
      B5DFN3
      UniProtKB/TrEMBL
      D3Z949

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      5204682..5217080 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279213.1XP_063135283.1  ubiquinol-cytochrome-c reductase complex assembly factor 2 isoform X1

    2. XM_039098811.2XP_038954739.1  ubiquinol-cytochrome-c reductase complex assembly factor 2 isoform X2

      UniProtKB/TrEMBL
      A0A8L2QIN0
    3. XM_063279214.1XP_063135284.1  ubiquinol-cytochrome-c reductase complex assembly factor 2 isoform X2

    4. XM_063279216.1XP_063135286.1  ubiquinol-cytochrome-c reductase complex assembly factor 2 isoform X3

      Related
      ENSRNOP00000036200.5, ENSRNOT00000036871.7
    5. XM_063279215.1XP_063135285.1  ubiquinol-cytochrome-c reductase complex assembly factor 2 isoform X3

    6. XM_039098812.2XP_038954740.1  ubiquinol-cytochrome-c reductase complex assembly factor 2 isoform X3

      UniProtKB/TrEMBL
      A0A8L2QIN0
    7. XM_039098813.2XP_038954741.1  ubiquinol-cytochrome-c reductase complex assembly factor 2 isoform X3

      UniProtKB/TrEMBL
      A0A8L2QIN0