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    Atp5f1e ATP synthase F1 subunit epsilon [ Rattus norvegicus (Norway rat) ]

    Gene ID: 245958, updated on 9-Dec-2024

    Summary

    Official Symbol
    Atp5f1eprovided by RGD
    Official Full Name
    ATP synthase F1 subunit epsilonprovided by RGD
    Primary source
    RGD:621374
    See related
    EnsemblRapid:ENSRNOG00000049912 AllianceGenome:RGD:621374
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Atp5e
    Summary
    Contributes to ATP hydrolysis activity. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Located in mitochondrial inner membrane. Part of proton-transporting ATP synthase complex, catalytic core F(1). Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Orthologous to several human genes including ATP5F1E (ATP synthase F1 subunit epsilon). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 5260.8), Heart (RPKM 5237.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Atp5f1e in Genome Data Viewer
    Location:
    3q43
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (183677270..183680172, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (163259072..163261974, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (172563105..172566007, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene negative elongation factor complex member C/D Neighboring gene cathepsin Z Neighboring gene tubulin, beta 1 class VI Neighboring gene PRELI domain containing 3B Neighboring gene uncharacterized LOC134486508

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in proton motive force-driven ATP synthesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in proton motive force-driven mitochondrial ATP synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in proton motive force-driven mitochondrial ATP synthesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ATP synthase subunit epsilon, mitochondrial
    Names
    ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
    ATPase subunit epsilon
    NP_620799.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139099.2NP_620799.1  ATP synthase subunit epsilon, mitochondrial

      See identical proteins and their annotated locations for NP_620799.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/Swiss-Prot
      P29418
      UniProtKB/TrEMBL
      A6KL35
      Related
      ENSRNOP00000067815.3, ENSRNOT00000071913.4
      Conserved Domains (1) summary
      pfam04627
      Location:350
      ATP-synt_Eps; Mitochondrial ATP synthase epsilon chain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      183677270..183680172 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)