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    Mcpt1l1 mast cell protease 1-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100360872, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mcpt1l1provided by RGD
    Official Full Name
    mast cell protease 1-like 1provided by RGD
    Primary source
    RGD:2321286
    See related
    EnsemblRapid:ENSRNOG00000053494 AllianceGenome:RGD:2321286
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mcpt1; rMCP-1; rMCP-I
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 131.4), Thymus (RPKM 75.6) and 7 other tissues See more
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    Genomic context

    See Mcpt1l1 in Genome Data Viewer
    Location:
    15p12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (33874239..33876895, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (29903993..29906649, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (34609785..34612441, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene mast cell protease 9 Neighboring gene mast cell protease 1 Neighboring gene mast cell protease 10 Neighboring gene cathepsin G

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    mast cell protease 1
    Names
    CLIP protein
    chymase
    chymotrypsin-like protease
    mast cell protease I
    protease 1-like
    NP_001264597.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001277668.1NP_001264597.1  mast cell protease 1 preproprotein

      See identical proteins and their annotated locations for NP_001264597.1

      Status: VALIDATED

      Source sequence(s)
      BM383497, FQ229802, U67915
      UniProtKB/Swiss-Prot
      P09650
      UniProtKB/TrEMBL
      A6KH81
      Related
      ENSRNOP00000069831.1, ENSRNOT00000090206.3
      Conserved Domains (2) summary
      smart00020
      Location:20239
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:21242
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      33874239..33876895 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)