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    Rpl7a ribosomal protein L7A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296596, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rpl7aprovided by RGD
    Official Full Name
    ribosomal protein L7Aprovided by RGD
    Primary source
    RGD:1307586
    See related
    EnsemblRapid:ENSRNOG00000070974 AllianceGenome:RGD:1307586
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in cellular response to Thyroid stimulating hormone. Located in ribosome. Part of cytosolic large ribosomal subunit. Orthologous to human RPL7A (ribosomal protein L7a). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 11.1), Spleen (RPKM 8.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rpl7a in Genome Data Viewer
    Location:
    3p13
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (30637136..30639778)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (10239026..10241703)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (5458985..5461627)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene surfeit 6 Neighboring gene mediator complex subunit 22 Neighboring gene small nucleolar RNA SNORD36 Neighboring gene small nucleolar RNA SNORD36 Neighboring gene small nucleolar RNA SNORD36 Neighboring gene small nucleolar RNA, C/D box 24 Neighboring gene SURF1, cytochrome c oxidase assembly factor Neighboring gene surfeit 2 Neighboring gene surfeit 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to Thyroid stimulating hormone IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in maturation of LSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
     
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein eL8
    Names
    60S ribosomal protein L7a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114391.1NP_001107863.1  large ribosomal subunit protein eL8

      See identical proteins and their annotated locations for NP_001107863.1

      Status: PROVISIONAL

      Source sequence(s)
      BC159421
      UniProtKB/Swiss-Prot
      P62425
      UniProtKB/TrEMBL
      A6JTI5, B0K021, B1WC55, D3ZU22, F1M013, F2Z3S2
      Related
      ENSRNOP00000063128.4, ENSRNOT00000044551.6
      Conserved Domains (1) summary
      PTZ00365
      Location:16266
      PTZ00365; 60S ribosomal protein L7Ae-like; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      30637136..30639778
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)