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    Sugp1 SURP and G patch domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 70616, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sugp1provided by MGI
    Official Full Name
    SURP and G patch domain containing 1provided by MGI
    Primary source
    MGI:MGI:1917866
    See related
    Ensembl:ENSMUSG00000011306 AllianceGenome:MGI:1917866
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sf4; 5730496N02Rik
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be part of spliceosomal complex. Predicted to be active in nucleoplasm. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human SUGP1 (SURP and G-patch domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 15.9), CNS E14 (RPKM 11.1) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Sugp1 in Genome Data Viewer
    Location:
    8 B3.3; 8 34.15 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (70495435..70524997)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (70042769..70072347)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_21762 Neighboring gene nucleoside diphosphate kinase B pseudogene Neighboring gene MAU2 sister chromatid cohesion factor Neighboring gene STARR-positive B cell enhancer ABC_E9314 Neighboring gene transmembrane 6 superfamily member 2 Neighboring gene hyaluronan and proteoglycan link protein 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    SURP and G-patch domain-containing protein 1
    Names
    splicing factor 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368391.1NP_001355320.1  SURP and G-patch domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      AC167132
      Consensus CDS
      CCDS22356.1
      UniProtKB/Swiss-Prot
      Q0VAT9, Q3U0W3, Q8CH02, Q8R094
    2. NM_027481.3NP_081757.1  SURP and G-patch domain-containing protein 1

      See identical proteins and their annotated locations for NP_081757.1

      Status: VALIDATED

      Source sequence(s)
      AC167132
      Consensus CDS
      CCDS22356.1
      UniProtKB/Swiss-Prot
      Q0VAT9, Q3U0W3, Q8CH02, Q8R094
      Related
      ENSMUSP00000011450.7, ENSMUST00000011450.8
      Conserved Domains (2) summary
      pfam01585
      Location:561605
      G-patch; G-patch domain
      pfam01805
      Location:186237
      Surp; Surp module

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      70495435..70524997
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030243755.2XP_030099615.1  SURP and G-patch domain-containing protein 1 isoform X1

      Conserved Domains (3) summary
      PRK12270
      Location:335458
      kgd; multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
      pfam01585
      Location:603645
      G-patch; G-patch domain
      pfam01805
      Location:227278
      Surp; Surp module
    2. XM_036154283.1XP_036010176.1  SURP and G-patch domain-containing protein 1 isoform X2

      Conserved Domains (3) summary
      PRK12270
      Location:87210
      kgd; multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
      pfam01585
      Location:355399
      G-patch; G-patch domain
      pfam01805
      Location:55106
      Surp; Surp module