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    Krt34 keratin 34 [ Mus musculus (house mouse) ]

    Gene ID: 16672, updated on 9-Dec-2024

    Summary

    Official Symbol
    Krt34provided by MGI
    Official Full Name
    keratin 34provided by MGI
    Primary source
    MGI:MGI:1309994
    See related
    Ensembl:ENSMUSG00000043485 AllianceGenome:MGI:1309994
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ha2; K34; Krt1-4; 4733401E01Rik
    Summary
    The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. [provided by RefSeq, Sep 2015]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See Krt34 in Genome Data Viewer
    Location:
    11 D; 11 63.38 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (99928173..99932380, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (100037347..100041554, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_30710 Neighboring gene keratin 33A Neighboring gene keratin 33B Neighboring gene keratin 31 Neighboring gene predicted gene 11571 Neighboring gene keratin 32

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in epithelial cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intermediate filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    keratin, type I cuticular Ha4
    Names
    hair keratin, type I Ha4
    keratin complex 1, acidic, gene 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027563.4NP_081839.1  keratin, type I cuticular Ha4

      See identical proteins and their annotated locations for NP_081839.1

      Status: REVIEWED

      Source sequence(s)
      AA755053, AK014631, AL592545
      Consensus CDS
      CCDS25404.1
      UniProtKB/Swiss-Prot
      Q9D646
      Related
      ENSMUSP00000056622.3, ENSMUST00000056362.3
      Conserved Domains (1) summary
      pfam00038
      Location:55366
      Filament; Intermediate filament protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      99928173..99932380 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)